Protein Alignment krz and Arrb2

DIOPT Version :10

• Sequence 1: NP_524988.1
• Gene: krz / 53554
• FlyBaseID: FBgn0040206
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_001258287.1
• Gene: Arrb2 / 216869
• MGIID: 99474
• Length: 421
• Species: Mus musculus
• Alignment Length: 428
• Identity: 254/428 - (59%)
• Similarity: 318/428 - (74%)
• Gaps: 19/428 - (4%)

  Fly    44 RQATRVFKKSSSNGKITVYLGKRDFVDHVTHVDPIDGVVFIDPEYVKDRKVFGQVLAAFRYGRED 108
            :..||||||||.|.|:||||||||||||:..|||:||||.:||:|:||||||..:..||||||||
Mouse     4 KPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGRED 68

  Fly   109 LDVLGLTFRKDLYLAHEQIYPPM-QLDRPMTRLQERLIKKLGPNAHPFYFEVPPYCPASVSLQPA 172
            ||||||:|||||::|..|.:||| ...||.||||:||:||||.:||||:|.:|...|.||:|||.
Mouse    69 LDVLGLSFRKDLFIATYQAFPPMPNPPRPPTRLQDRLLKKLGQHAHPFFFTIPQNLPCSVTLQPG 133

  Fly   173 PGDVGKSCGVDYELKAFVGENVEDKPHKRNSVRLTIRKVMYAPSKVGEQPSIEVSKEFMMKPNK- 236
            |.|.||:||||:|::||..:::|:|.||||||||.||||.:||...|.|||.|.::.|:|...:
Mouse   134 PEDTGKACGVDFEIRAFCAKSIEEKSHKRNSVRLIIRKVQFAPETPGPQPSAETTRHFLMSDRRS 198

  Fly   237 IHLEATLDKELYHHGEKISVNVHVANNSNRTVKKIKVCVRQFADICLFSTAQYKSVVAEIESEDG 301
            :||||:||||||:|||.::|||||.|||.:|||||:|.|||:||||||||||||..||::|.:|
Mouse   199 LHLEASLDKELYYHGEPLNVNVHVTNNSAKTVKKIRVSVRQYADICLFSTAQYKCPVAQLEQDD- 262

  Fly   302 CQVAPGFTLSKVFELCPLLANNKDKWGLALDGQLKHEDTNLASSTLITNPAQRESLGIMVHYKVK 366
             ||:|..|..||:.:.|||::|::|.|||||||||||||||||||::...|.:|.|||:|.|:||
Mouse   263 -QVSPSSTFCKVYTITPLLSDNREKRGLALDGQLKHEDTNLASSTIVKEGANKEVLGILVSYRVK 326

  Fly   367 VKLLISSPLLNGDLVAELPFTLMHPKPEEEEHPLLGERSPRASLAGGGLPLVSMSDGETESATGG 431
            |||::|.   .||:..||||.||||||  .:|..|    ||...|....||:      ..||...
Mouse   327 VKLVVSR---GGDVSVELPFVLMHPKP--HDHITL----PRPQSAPIHPPLL------CPSAPRE 376

  Fly   432 QDVPTTTNLIQLDDDEAQDDDIIFEDFARLRLKGAETE 469
            .|||..||||:.|.:.|.||||:|||||||||||.:.:
Mouse   377 TDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDD 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
krz	NP_524988.1	Arrestin_N	59..214	CDD:451447	101/155 (65%)
		Arrestin_C	233..393	CDD:214976	99/160 (62%)
Arrb2	NP_001258287.1	Arrestin_N	19..175	CDD:451447	101/155 (65%)
		Arrestin_C	199..350	CDD:214976	99/155 (64%)