DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment krz and Arr3

DIOPT Version :9

Sequence 1:	NP_001247400.1	Gene:	krz / 53554	FlyBaseID:	FBgn0040206	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001177922.1	Gene:	Arr3 / 171107	RGDID:	621385	Length:	381	Species:	Rattus norvegicus

Alignment Length:	368	Identity:	178/368 - (48%)
Similarity:	248/368 - (67%)	Gaps:	15/368 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VFKKSSSNGKITVYLGKRDFVDHVTHVDPIDGVVFIDPEYVKDRKVFGQVLAAFRYGREDLDVLG 113
            ||||:|||||.::|||||||||.|..|:|||||:.:||||:|.||:|.::..||||||:||||:|
  Rat     4 VFKKTSSNGKFSIYLGKRDFVDDVDTVEPIDGVILVDPEYLKGRKMFVRLTCAFRYGRDDLDVIG 68

  Fly   114 LTFRKDLYLAHEQIYP--PMQLDRPMTRLQERLIKKLGPNAHPFYFEVPPYCPASVSLQPAPGDV 176
            ||||||||:..:|:.|  |..:..|:|.|||||:.|||.||:||..::....|.||:|||.|.|.
  Rat    69 LTFRKDLYVQTKQVAPAEPTSIQGPLTALQERLLHKLGVNAYPFTLQMVANLPCSVTLQPGPEDS 133

  Fly   177 GKSCGVDYELKAFVGENVEDKPHKRNSVRLTIRKVMYAPSKVGEQPSIEVSKEFMMKPNKIHLEA 241
            ||.||||:|:|:|..||:|:|..|.:||:|.:|||.::..:.|..|..:..:.|.:....:.|:|
  Rat   134 GKPCGVDFEVKSFCAENLEEKISKSDSVQLVVRKVQFSALEPGPGPWAQTIRSFFLSSQPLQLQA 198

  Fly   242 TLDKELYHHGEKISVNVHVANNSNRTVKKIKVCVRQFADICLFSTAQYKSVVAEIESEDGCQVAP 306
            .:|:|:::|||.|||:|.:.|.:|:.:::||:.|.|..|:.|:|..:|...|...|..:  .||.
  Rat   199 WMDREVHYHGEAISVHVSINNYTNKVIRRIKIAVIQITDVVLYSLDKYTKTVFIREFTE--TVAA 261

  Fly   307 GFTLSKVFELCPLLANNKDKWGLALDGQLKHEDTNLASSTLITNPAQRESLGIMVHYKVKVKLLI 371
            ..:.|:.|.:.||||.|:.|.||||||:||||||||||||::.....:|.|||:|.|||||.|::
  Rat   262 NSSFSQTFAVTPLLAANRQKQGLALDGKLKHEDTNLASSTILRPGMNKELLGILVSYKVKVNLMV 326

  Fly   372 S-SPLLNG----DLVAELPFTLMHPKPEEEEHPLLGERSPRAS 409
            | ..:|.|    |:..|||..|:||||..      |||:...|
  Rat   327 SYGGILGGLPASDVGVELPLILIHPKPPH------GERAVATS 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
krz	NP_001247400.1	Arrestin_N	59..214	CDD:419887	88/156 (56%)
krz	NP_001247400.1	Arrestin_C	233..393	CDD:214976	72/164 (44%)
Arr3	NP_001177922.1	Arrestin_N	14..171	CDD:278754	88/156 (56%)
Arr3	NP_001177922.1	Arrestin_C	190..353	CDD:214976	72/164 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353563
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.810