DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment krz and arr3

DIOPT Version :9

Sequence 1:	NP_001247400.1	Gene:	krz / 53554	FlyBaseID:	FBgn0040206	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	XP_012823333.1	Gene:	arr3 / 100124859	XenbaseID:	XB-GENE-966159	Length:	387	Species:	Xenopus tropicalis

Alignment Length:	431	Identity:	193/431 - (44%)
Similarity:	272/431 - (63%)	Gaps:	58/431 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 QATRVFKKSSSNGKITVYLGKRDFVDHVTHVDPIDGVVFIDPEYVKDRKVFGQVLAAFRYGREDL 109
            :.::||||||::||:::||.|||:||||.||:|:||::.|||||.||:|||..:...|||||:|.
Frog     3 EGSKVFKKSSADGKLSIYLAKRDYVDHVDHVEPVDGMILIDPEYQKDKKVFVTLTCTFRYGRDDH 67

  Fly   110 DVLGLTFRKDLYLAHEQIYPPMQLD-RPMTRLQERLIKKLGPNAHPFYFEVPPYCPASVSLQPAP 173
            :::||:|:||||..|.|:|||:..| :.:|.|||:|.||||.||.||.|.:....|.||:|||.|
Frog    68 ELIGLSFKKDLYFLHCQVYPPLPEDKKALTPLQEKLAKKLGQNAFPFCFNMATDLPCSVTLQPGP 132

  Fly   174 GDVGKSCGVDYELKAFVGENVEDKPHKRNSVRLTIRKVMYAPSKVGEQPSIEVSKEFMMKPNKIH 238
            .|.||.||||:|:|.|..||||:|..::|||:|.||||.:||...|..|.::.:::|||....:.
Frog   133 EDTGKKCGVDFEVKGFCAENVEEKVPRKNSVQLIIRKVQFAPEATGPAPCVQTTRQFMMSDRPLQ 197

  Fly   239 LEATLDKELYHHGEKISVNVHVANNSNRTVKKIKVCVRQFADICLFSTAQYKSVVAEIESEDGCQ 303
            |||:|:||:|:|||.|.|||.:.||:::.|||||:.|.|..|:.|:|..:|..:|...|..|  .
Frog   198 LEASLNKEIYYHGEPIGVNVKITNNTSKIVKKIKITVEQLTDVVLYSLDKYTKIVCCEEMND--T 260

  Fly   304 VAPGFTLSKVFELCPLLANNKDKWGLALDGQLKHEDTNLASSTLITNPAQRESLGIMVHYKVKVK 368
            ||...|.|..:.:.||||||::|.||||||:|||.||||||||::.....:|.||::|.|||:|.
Frog   261 VAANGTFSGSYSVTPLLANNREKRGLALDGKLKHGDTNLASSTILRPGMDKEVLGMLVSYKVRVN 325

  Fly   369 LLIS-----SPLLNGDLVAELPFTLMHPKPEEEEHPLLGERSPRASLAGGGLPLVSMSDGETESA 428
            |:::     ..|.:.|::.:||.|||||||.
Frog   326 LVVARGGILGDLTSSDVLVDLPLTLMHPKPS---------------------------------- 356

  Fly   429 TGGQDVPTTTNLIQLDDDEAQDDDIIFEDFARLRLKGAETE 469
                  |..||:          :|::.|:|||.:|:|||.|
Frog   357 ------PDQTNI----------EDVVIEEFARQKLQGAEGE 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
krz	NP_001247400.1	Arrestin_N	59..214	CDD:419887	87/155 (56%)
krz	NP_001247400.1	Arrestin_C	233..393	CDD:214976	76/164 (46%)
arr3	XP_012823333.1	Arrestin_N	17..173	CDD:334019	87/155 (56%)
arr3	XP_012823333.1	Arrestin_C	192..355	CDD:214976	76/164 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	227	1.000	Domainoid score	I2445
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	487	1.000	Inparanoid score	I1402
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	1	1.000	-	-		FOG0000854
OrthoInspector	1	1.000	-	-		otm48094
Panther	1	1.100	-	-	O	PTHR11792
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X758
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160