DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lectin-21Ca and acanb

DIOPT Version :9

Sequence 1:	NP_652642.2	Gene:	lectin-21Ca / 53552	FlyBaseID:	FBgn0040107	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	XP_021326217.1	Gene:	acanb / 559593	ZFINID:	ZDB-GENE-100422-16	Length:	1376	Species:	Danio rerio

Alignment Length:	305	Identity:	60/305 - (19%)
Similarity:	91/305 - (29%)	Gaps:	104/305 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 TDKEVCLVELAPVLKYISNNHKSHWNSANEVQVNETRKQLAKIEGQ----EKETNDKIKVIHDNV 91
            ||.||..:.|.|...                  .|..:...:|.|:    |..|.|.|.| .::.
Zfish  1014 TDDEVTELTLRPTAG------------------TEQGRGSVEISGEGSTPEPYTEDSISV-SNST 1059

  Fly    92 DNEFNAL--------------------SAKIKNVKNIQRHLASLELQLQETKKALNLSVEAKKVM 136
            .:|.|.|                    |..|....||..........||..|..:|.||
Zfish  1060 SHESNDLLPERDEKISVTMEAFDVTDKSPLITTPTNIPVLTTPSSASLQMPKSTMNPSV------ 1118

  Fly   137 PKTEIPS-------------------------------------QFQKIGWRHF----FIEKKHK 160
              .|.||                                     |....||..|    :|....:
Zfish  1119 --NEAPSDPCDPNPCGQGLCSLQDGVALCQCHSGFSGENCSVLVQGCAEGWMEFMGSCYIHFDER 1181

  Fly   161 VDWFKATSMCHKMGAHLLTIQSEDELDAIRTELKDINDGSHDFWLDINDIAKWGEFISLATGMNP 225
            ..|..|...|.::.:||::|.|:.|.:.::|:.:|..      |:.:||.....|| ....|...
Zfish  1182 ETWTSAEQHCQELNSHLVSISSQQEQEFVKTQAQDYQ------WIGLNDKDVQNEF-RWTDGSPL 1239

  Fly   226 PFLKWHKHRPQ--VQIHQRCVHL---RGGEMMDGKCSEQFLFICQ 265
            .:..|..::|.  ....:.||.:   ..|:..|..|:....|.|:
Zfish  1240 EYENWRPNQPDNYFSTGEDCVVMIWHENGQWNDVPCNYHLPFTCK 1284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-21Ca	NP_652642.2	CLECT	158..265	CDD:153057	24/111 (22%)
acanb	XP_021326217.1	Ig	45..159	CDD:325142
		Link_domain_CSPGs_modules_1_3	158..252	CDD:239594
		Link_domain_CSPGs_modules_2_4	260..354	CDD:239597
		Xlink	459..553	CDD:306661
		Link_domain_CSPGs_modules_2_4	560..655	CDD:239597
		CLECT	1163..1284	CDD:321932	28/127 (22%)
		CCP	1290..1347	CDD:153056
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4956
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940