DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-21Ca and CLEC4E

DIOPT Version :9

Sequence 1:	NP_652642.2	Gene:	lectin-21Ca / 53552	FlyBaseID:	FBgn0040107	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_055173.1	Gene:	CLEC4E / 26253	HGNCID:	14555	Length:	219	Species:	Homo sapiens

Alignment Length:	173	Identity:	31/173 - (17%)
Similarity:	58/173 - (33%)	Gaps:	65/173 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 KTEIPSQFQK----------------IGWRHF----FIEKKHKVDWFKATSMCHKMGAHLLTIQS 182
            |.::|..|.:                :.|.:|    :......:.|..:...|..|||||:.|.|
Human    56 KFQLPENFTELSCYNYGSGSVKNCCPLNWEYFQSSCYFFSTDTISWALSLKNCSAMGAHLVVINS 120

  Fly   183 EDELDAI---RTELKDINDGSHD-------FWLDINDIAK----W--GEFISLAT--------GM 223
            ::|.:.:   :.::::...|..|       .|:|...:.|    |  ||..::||        ..
Human   121 QEEQEFLSYKKPKMREFFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEPNNIATLEDCATMRDS 185

  Fly   224 NPPFLKWHKHRPQVQIHQRCVHLRGGEMMDGKCSEQFLFICQL 266
            :.|...|:                     |..|...:..||::
Human   186 SNPRQNWN---------------------DVTCFLNYFRICEM 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-21Ca	NP_652642.2	CLECT	158..265	CDD:153057	25/130 (19%)
CLEC4E	NP_055173.1	CLECT_DC-SIGN_like	80..207	CDD:153060	28/147 (19%)
CLEC4E	NP_055173.1	Confers specificity for glucose/mannose-type carbohydrates. /evidence=ECO:0000303\|PubMed:24101491	169..171		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11773
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010