DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-24Db and CD72

DIOPT Version :9

Sequence 1:	NP_652641.1	Gene:	lectin-24Db / 53550	FlyBaseID:	FBgn0040102	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	XP_006716956.1	Gene:	CD72 / 971	HGNCID:	1696	Length:	366	Species:	Homo sapiens

Alignment Length:	358	Identity:	64/358 - (17%)
Similarity:	106/358 - (29%)	Gaps:	134/358 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CIVYLLVACNLVESRAESTENSRSVCLLKDPPNQCGEFCLSVLQPLLDHIVKHQEQWNTSEALWL 71
            |:.|||:...|             .|||..    ....||.|     .::...|:...|:..|.:
Human    92 CLRYLLLGLLL-------------TCLLLG----VTAICLGV-----RYLQVSQQLQQTNRVLEV 134

  Fly    72 NETQGKLDRIQTQLAAQALSLEESAQKVPGDIKDRLDRMEHLQTTLQESLKKMPAELDARLMKME 136
            ..:.     ::.||..:...|.:||:.:.|..::.....|.||.
Human   135 TNSS-----LRQQLRLKITQLGQSAEDLQGSRRELAQSQEALQV--------------------- 173

  Fly   137 NQQKTLGDQLENQINLTKESQQDQLEALKNAMPINFEMRLAQIEEQQKLLQETLKKIPEDFERKL 201
              ::......|.|:...:..:|...|.|             |.||||:          ...|:||
Human   174 --EQRAHQAAEGQLQACQADRQKTKETL-------------QSEEQQR----------RALEQKL 213

  Fly   202 QKLEQNQKDELTKLGAQQSANQVTLKEIYTKVFWPKFERIGSRLFYINHKDAYDWQSAVDFCRDM 266
            ..:|...|...|...|......          .|...::   ..|||: ..:.:||.:...|..:
Human   214 SNMENRLKPFFTCGSADTCCPS----------GWIMHQK---SCFYIS-LTSKNWQESQKQCETL 264

  Fly   267 GGYIAAIKD----QEELDAISARLDD----KSYWLGINDLQSSNTYVSVASGREVEFLNWNAGEP 323
            ...:|...:    ......:::.|.:    .|||.|:    |||.             :|
Human   265 SSKLATFSEIYPQSHSYYFLNSLLPNGGSGNSYWTGL----SSNK-------------DW----- 307

  Fly   324 NHGNEDENCVELIRSKMNDDPCHRKKHVICQTD 356
                           |:.|| ..|.:| .||.:
Human   308 ---------------KLTDD-TQRTRH-SCQQE 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24Db	NP_652641.1	ExsD	<44..>156	CDD:293411	17/111 (15%)
		NAT_SF	<170..>229	CDD:302625	12/58 (21%)
		CLECT	247..354	CDD:153057	20/114 (18%)
CD72	XP_006716956.1	DMPK_coil	168..223	CDD:117396	18/100 (18%)
CD72	XP_006716956.1	CLECT	233..>319	CDD:214480	22/138 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000