DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-24Db and Clec4e

DIOPT Version :9

Sequence 1:	NP_652641.1	Gene:	lectin-24Db / 53550	FlyBaseID:	FBgn0040102	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_001005897.2	Gene:	Clec4e / 450223	RGDID:	1359298	Length:	215	Species:	Rattus norvegicus

Alignment Length:	127	Identity:	32/127 - (25%)
Similarity:	55/127 - (43%)	Gaps:	11/127 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 WPKFERIGSRLFYINHKDAYDWQSAVDFCRDMGGYIAAIKDQEELDAI-SARLDDKSYWLGINDL 298
            |..|:   |..::.: .....|.|:::.|.|||.::..|...||.:.: ..:...|.:::|:.|.
  Rat    85 WKHFQ---SSCYFFS-TTTLTWPSSLNNCSDMGAHLVVINTWEEQEFLFRTKPRKKEFYIGLTDQ 145

  Fly   299 QSSNTYVSVASGREVEFLN-WNAGEPNHGNEDENCVEL-----IRSKMNDDPCHRKKHVICQ 354
            .....:..|......|.|: |:|||||:....|:|..:     .|...||..|......||:
  Rat   146 VVEGQWRWVDDTPFTESLSFWDAGEPNNIVFVEDCATMRDSSNPRKNWNDVSCFFSMPWICE 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24Db	NP_652641.1	ExsD	<44..>156	CDD:293411
		NAT_SF	<170..>229	CDD:302625
		CLECT	247..354	CDD:153057	28/113 (25%)
Clec4e	NP_001005897.2	CLECT_DC-SIGN_like	81..208	CDD:153060	32/127 (25%)
Clec4e	NP_001005897.2	Confers specificity for glucose/mannose-type carbohydrates. /evidence=ECO:0000250\|UniProtKB:Q9ULY5	170..172		1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010