Protein Alignment lectin-24Db and CLEC4E

DIOPT Version :10

• Sequence 1: NP_652641.1
• Gene: lectin-24Db / 53550
• FlyBaseID: FBgn0040102
• Length: 359
• Species: Drosophila melanogaster
• Sequence 2: NP_055173.1
• Gene: CLEC4E / 26253
• HGNCID: 14555
• Length: 219
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 42/199 - (21%)
• Similarity: 75/199 - (37%)
• Gaps: 58/199 - (29%)

  Fly   175 RLAQIEEQQKLLQETLKKIPEDFERKLQKLEQNQKDELT--KLGAQQSANQVTLKEIYTKVFWPK 237
            |:.|..:::|.      ::||:|            .||:  ..|:....|...|.       |..
Human    47 RIFQTCDEKKF------QLPENF------------TELSCYNYGSGSVKNCCPLN-------WEY 86

  Fly   238 FERIGSRLFYINHKDAYDWQSAVDFCRDMGGYIAAIKDQEELDAISARLDD-KSYWLGINDLQSS 301
            |:   |..::.: .|...|..::..|..||.::..|..|||.:.:|.:... :.:::|::|
Human    87 FQ---SSCYFFS-TDTISWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPKMREFFIGLSD---- 143

  Fly   302 NTYVSVASG-----------REVEFLNWNAGEPNHGNEDENCVEL-----IRSKMNDDPCHRKKH 350
                .|..|           :.:.|  |:.||||:....|:|..:     .|...||..|.....
Human   144 ----QVVEGQWQWVDGTPLTKSLSF--WDVGEPNNIATLEDCATMRDSSNPRQNWNDVTCFLNYF 202

  Fly   351 VICQ 354
            .||:
Human   203 RICE 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24Db	NP_652641.1	IFT57	<64..215	CDD:463118	8/41 (20%)
		CLECT	247..354	CDD:153057	27/123 (22%)
CLEC4E	NP_055173.1	CLECT_DC-SIGN_like	80..207	CDD:153060	32/148 (22%)
		Confers specificity for glucose/mannose-type carbohydrates. /evidence=ECO:0000303|PubMed:24101491	169..171		1/1 (100%)