DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lectin-24Db and CLEC4E

DIOPT Version :9

Sequence 1:	NP_652641.1	Gene:	lectin-24Db / 53550	FlyBaseID:	FBgn0040102	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_055173.1	Gene:	CLEC4E / 26253	HGNCID:	14555	Length:	219	Species:	Homo sapiens

Alignment Length:	199	Identity:	42/199 - (21%)
Similarity:	75/199 - (37%)	Gaps:	58/199 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 RLAQIEEQQKLLQETLKKIPEDFERKLQKLEQNQKDELT--KLGAQQSANQVTLKEIYTKVFWPK 237
            |:.|..:::|.      ::||:|            .||:  ..|:....|...|.       |..
Human    47 RIFQTCDEKKF------QLPENF------------TELSCYNYGSGSVKNCCPLN-------WEY 86

  Fly   238 FERIGSRLFYINHKDAYDWQSAVDFCRDMGGYIAAIKDQEELDAISARLDD-KSYWLGINDLQSS 301
            |:   |..::.: .|...|..::..|..||.::..|..|||.:.:|.:... :.:::|::|
Human    87 FQ---SSCYFFS-TDTISWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPKMREFFIGLSD---- 143

  Fly   302 NTYVSVASG-----------REVEFLNWNAGEPNHGNEDENCVEL-----IRSKMNDDPCHRKKH 350
                .|..|           :.:.|  |:.||||:....|:|..:     .|...||..|.....
Human   144 ----QVVEGQWQWVDGTPLTKSLSF--WDVGEPNNIATLEDCATMRDSSNPRQNWNDVTCFLNYF 202

  Fly   351 VICQ 354
            .||:
Human   203 RICE 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24Db	NP_652641.1	ExsD	<44..>156	CDD:293411
		NAT_SF	<170..>229	CDD:302625	11/55 (20%)
		CLECT	247..354	CDD:153057	27/123 (22%)
CLEC4E	NP_055173.1	CLECT_DC-SIGN_like	80..207	CDD:153060	32/148 (22%)
CLEC4E	NP_055173.1	Confers specificity for glucose/mannose-type carbohydrates. /evidence=ECO:0000303\|PubMed:24101491	169..171		1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010