DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lectin-24Db and Sftpd

DIOPT Version :9

Sequence 1:	NP_652641.1	Gene:	lectin-24Db / 53550	FlyBaseID:	FBgn0040102	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_033186.1	Gene:	Sftpd / 20390	MGIID:	109515	Length:	374	Species:	Mus musculus

Alignment Length:	168	Identity:	40/168 - (23%)
Similarity:	74/168 - (44%)	Gaps:	23/168 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 LKKIPEDFERKLQKLEQNQKDELTKLGAQQSANQVTLKEIYTKVFWPKFERIGSRLFYINHKDAY 254
            |::..|..:.|||:||                  |..........:|....:|.::|.....:.
Mouse   226 LRQQMEALKGKLQRLE------------------VAFSHYQKAALFPDGRSVGDKIFRTADSEK- 271

  Fly   255 DWQSAVDFCRDMGGYIAAIKDQEELDAISARL--DDKSYWLGINDLQSSNTYVSVASGREVEFLN 317
            .::.|.:.|:..||.:|:.:...|..||...:  .:|:.:|.:.|:.:...: :..:|..:.:.|
Mouse   272 PFEDAQEMCKQAGGQLASPRSATENAAIQQLITAHNKAAFLSMTDVGTEGKF-TYPTGEPLVYSN 335

  Fly   318 WNAGEPNHGNEDENCVELI-RSKMNDDPCHRKKHVICQ 354
            |..||||:....|||||:. ..:.||..|..::.|||:
Mouse   336 WAPGEPNNNGGAENCVEIFTNGQWNDKACGEQRLVICE 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24Db	NP_652641.1	ExsD	<44..>156	CDD:293411
		NAT_SF	<170..>229	CDD:302625	8/38 (21%)
		CLECT	247..354	CDD:153057	28/109 (26%)
Sftpd	NP_033186.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..222
		Collagen	45..102	CDD:189968
		Collagen	129..>171	CDD:189968
		Surfac_D-trimer	223..267	CDD:286141	11/58 (19%)
		CLECT_collectin_like	261..374	CDD:153061	30/115 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910