DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-24Db and Selp

DIOPT Version :9

Sequence 1:	NP_652641.1	Gene:	lectin-24Db / 53550	FlyBaseID:	FBgn0040102	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_035477.1	Gene:	Selp / 20344	MGIID:	98280	Length:	768	Species:	Mus musculus

Alignment Length:	147	Identity:	43/147 - (29%)
Similarity:	70/147 - (47%)	Gaps:	31/147 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 KVFWPKFERIGSRLFYINHKD-----------AYDWQSAVDFCRDMGGYIAAIKDQEELDAISAR 285
            ::.|  |..:.|.|  :|.|:           ||.|.::..|||.....:.||:::.|:    |.
Mouse    22 QLIW--FSALISEL--VNQKEVAAWTYNYSTKAYSWNNSRVFCRRHFTDLVAIQNKNEI----AH 78

  Fly   286 LDD------KSYWLGINDLQSSNTYVSVASGREVEFLNWNAGEPNHGNEDENCVEL-IRS----- 338
            |:|      ..||:||..:.:..|:|........|..||...|||:...:::|||: |:|
Mouse    79 LNDVIPFFNSYYWIGIRKINNKWTWVGTNKTLTEEAENWADNEPNNKKNNQDCVEIYIKSNSAPG 143

  Fly   339 KMNDDPCHRKKHVICQT 355
            |.||:||.::|..:|.|
Mouse   144 KWNDEPCFKRKRALCYT 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24Db	NP_652641.1	ExsD	<44..>156	CDD:293411
		NAT_SF	<170..>229	CDD:302625
		CLECT	247..354	CDD:153057	37/129 (29%)
Selp	NP_035477.1	CLECT_selectins_like	42..160	CDD:153062	36/121 (30%)
		EGF_CA	<168..195	CDD:238011
		CCP	200..257	CDD:153056
		CCP	262..320	CDD:153056
		CCP	324..382	CDD:153056
		CCP	386..444	CDD:153056
		CCP	448..506	CDD:153056
		CCP	510..568	CDD:153056
		CCP	580..638	CDD:153056
		CCP	642..700	CDD:153056
		Endocytosis signal. /evidence=ECO:0000305	756..759
		Interaction with SNX17. /evidence=ECO:0000250	759..768
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9758
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910