DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-24Db and CLEC3A

DIOPT Version :9

Sequence 1:	NP_652641.1	Gene:	lectin-24Db / 53550	FlyBaseID:	FBgn0040102	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_005743.5	Gene:	CLEC3A / 10143	HGNCID:	2052	Length:	197	Species:	Homo sapiens

Alignment Length:	203	Identity:	53/203 - (26%)
Similarity:	87/203 - (42%)	Gaps:	59/203 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 LLQETLK-----KIPEDFERKLQKLEQNQKDELTKLGAQQSANQVTLKEIY---------TKVFW 235
            ||.:|..     |..:..:|:::..:.:.|.::.||..:.:|    ||||.         |||
Human    16 LLDQTTSHTSRLKARKHSKRRVRDKDGDLKTQIEKLWTEVNA----LKEIQALQTVCLRGTKV-- 74

  Fly   236 PKFERIGSRLFYINHKDAY-------DWQSAVDFCRDMGGYIAAIKDQEELDAISARLDD----- 288
                          ||..|       .:..|.:.|...||.:...::.:|::|    |.|
Human    75 --------------HKKCYLASEGLKHFHEANEDCISKGGILVIPRNSDEINA----LQDYGKRS 121

  Fly   289 ----KSYWLGINDLQSSNTYVSVASGREVEFLNWNAGEPNHGNEDENCV---ELIRSKMNDDPCH 346
                ..:||||||:.:...:|.| :|..:.||||:..:|| |.:.||||   :..:.|.:|:.|.
Human   122 LPGVNDFWLGINDMVTEGKFVDV-NGIAISFLNWDRAQPN-GGKRENCVLFSQSAQGKWSDEACR 184

  Fly   347 RKKHVICQ 354
            ..|..||:
Human   185 SSKRYICE 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24Db	NP_652641.1	ExsD	<44..>156	CDD:293411
		NAT_SF	<170..>229	CDD:302625	11/48 (23%)
		CLECT	247..354	CDD:153057	36/125 (29%)
CLEC3A	NP_005743.5	CLECT_tetranectin_like	68..193	CDD:153066	40/147 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910