DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-29Ca and SFTPD

DIOPT Version :9

Sequence 1:	NP_652640.1	Gene:	lectin-29Ca / 53547	FlyBaseID:	FBgn0040098	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	NP_003010.4	Gene:	SFTPD / 6441	HGNCID:	10803	Length:	375	Species:	Homo sapiens

Alignment Length:	153	Identity:	31/153 - (20%)
Similarity:	58/153 - (37%)	Gaps:	18/153 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 ALKQQIEPYMENVK-----MSNKIKMSVF---KKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLA 149
            :|:||:|.....|:     .|...|:.:|   :.:|.:.|......| |:..|...|.|.||.||
Human   226 SLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVK-PFTEAQLLCTQAGGQLA 289

  Fly   150 ---NILDEKELNEIFSEETKKKYWVDINSRANDGASWISTLSGRDVPFLKWKPNLATNI--HNHC 209
               :..:...|.::...:.:..: :.:.....:|.....|  |..:.:..|.|....:.  ...|
Human   290 SPRSAAENAALQQLVVAKNEAAF-LSMTDSKTEGKFTYPT--GESLVYSNWAPGEPNDDGGSEDC 351

  Fly   210 VYINSNEMYFEN-CANDNYFACQ 231
            |.|.:|..:.:. |.......|:
Human   352 VEIFTNGKWNDRACGEKRLVVCE 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-29Ca	NP_652640.1	CLECT	131..231	CDD:153057	20/105 (19%)
SFTPD	NP_003010.4	Collagen	46..98	CDD:189968
		Collagen	130..201	CDD:189968
		Surfac_D-trimer	224..269	CDD:286141	10/42 (24%)
		CLECT_collectin_like	262..375	CDD:153061	22/117 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11773
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910