DRSC/TRiP Functional Genomics Resources

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Protein Alignment lectin-29Ca and CLEC4A

DIOPT Version :9

Sequence 1:NP_652640.1 Gene:lectin-29Ca / 53547 FlyBaseID:FBgn0040098 Length:236 Species:Drosophila melanogaster
Sequence 2:NP_057268.1 Gene:CLEC4A / 50856 HGNCID:13257 Length:237 Species:Homo sapiens


Alignment Length:174 Identity:33/174 - (18%)
Similarity:66/174 - (37%) Gaps:35/174 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    81 QSFQNQMETKLRALKQQIEPYMENVKMSNKIKMSVFK------KIGSRHFYLEKQKKMPWDSAYD 139
            |.:...:|.|  ..|:.:...:|.||.:..::.:.:.      |..|.:.|....:...|..:..
Human    70 QKYSQLLEKK--TTKELVHTTLECVKKNMPVEETAWSCCPKNWKSFSSNCYFISTESASWQDSEK 132

  Fly   140 TCRQMGGHLANILDEKELNEIFSE-ETKKKYWVDINSRANDGA---SWISTLSGRDVPFLK---- 196
            .|.:|..||..|..::|.:.||.. :.:..|:|.::.  .:|.   .|:.     ..|:.:    
Human   133 DCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSD--PEGQRHWQWVD-----QTPYNESSTF 190

  Fly   197 WKPNLATNIHNHCVYINS---------NEMYFENCANDNYFACQ 231
            |.|...::.:..||.:|.         |::   ||.......|:
Human   191 WHPREPSDPNERCVVLNFRKSPKRWGWNDV---NCLGPQRSVCE 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lectin-29CaNP_652640.1 CLECT 131..231 CDD:153057 22/116 (19%)
CLEC4ANP_057268.1 ITIM motif. /evidence=ECO:0000269|PubMed:20530286 5..10
CLECT_DC-SIGN_like 106..232 CDD:153060 26/136 (19%)
Mannose binding. /evidence=ECO:0000269|PubMed:27015765, ECO:0007744|PDB:5B1X 195..197 0/1 (0%)
N-acetyl-D-glucosamine binding. /evidence=ECO:0000269|PubMed:27015765, ECO:0007744|PDB:5B1X 207..209 1/1 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 49 1.000 Domainoid score I11773
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR22802
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
33.010

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