DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-29Ca and CLEC17A

DIOPT Version :9

Sequence 1:	NP_652640.1	Gene:	lectin-29Ca / 53547	FlyBaseID:	FBgn0040098	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	NP_001191047.1	Gene:	CLEC17A / 388512	HGNCID:	34520	Length:	378	Species:	Homo sapiens

Alignment Length:	215	Identity:	51/215 - (23%)
Similarity:	82/215 - (38%)	Gaps:	41/215 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 QQHWFTYNSLRQNGTLW---------RIGNMEQRLEMRLQSFQNQMETK--------LRALKQQI 98
            |:.|..|..|....:|:         .|...|...|:|:.||| ||..:        |..||..|
Human   166 QKRWMVYLCLLVVTSLFLGCLGLTVTLIKYQELMEELRMLSFQ-QMTWRTNMTGMAGLAGLKHDI 229

  Fly    99 EPYMENVKMSNKIKMSVFKKIGSRH--------------FYLEKQKKMPWDSAYDTCRQMGGHLA 149
            .....:   :|:..:.::..:..|.              :|.....| .||.|...|::...||.
Human   230 ARVRAD---TNQSLVELWGLLDCRRITCPEGWLPFEGKCYYFSPSTK-SWDEARMFCQENYSHLV 290

  Fly   150 NILDEKELNEIF-SEETKKKYWVDINSRANDGASWISTLSGRDVPFLKWKPNLATNIHNH-CVYI 212
            .|....|.|.:. :..:.:.||:.:|.||.:| .| ..|.|..|....|:|....|||:. |..:
Human   291 IINSFAEHNFVAKAHGSPRVYWLGLNDRAQEG-DW-RWLDGSPVTLSFWEPEEPNNIHDEDCATM 353

  Fly   213 NSNEMYFE-NCANDNYFACQ 231
            |....:.: :|....|:.|:
Human   354 NKGGTWNDLSCYKTTYWICE 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-29Ca	NP_652640.1	CLECT	131..231	CDD:153057	29/102 (28%)
CLEC17A	NP_001191047.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..119
CLEC17A	NP_001191047.1	CLECT_DC-SIGN_like	254..374	CDD:153060	31/123 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X29
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910