DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-24A and COLEC11

DIOPT Version :9

Sequence 1:	NP_652637.1	Gene:	lectin-24A / 53543	FlyBaseID:	FBgn0040104	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_001242914.1	Gene:	COLEC11 / 78989	HGNCID:	17213	Length:	285	Species:	Homo sapiens

Alignment Length:	159	Identity:	41/159 - (25%)
Similarity:	68/159 - (42%)	Gaps:	17/159 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 QLEAIKNTMDYMKAQMDGYFSAI-NGVQCLQPGFEKIGDRYFYIEEDVELNWLDAQAKCRRMGGH 193
            ||......||...:|:......| |.|..::....||   |..::|  |..:.|||..|:..||.
Human   131 QLRKAIGEMDNQVSQLTSELKFIKNAVAGVRETESKI---YLLVKE--EKRYADAQLSCQGRGGT 190

  Fly   194 LASIKTKQEFDAIVEKLDDS--KSYFLGVNENTKTGDFVSAASGKSCLYHEWGPGEPHHNNDQER 256
            |:..|.:.....:...|..:  ...|:|:|:..|.|.||.:.......:::|..|||::..|:|.
Human   191 LSMPKDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEED 255

  Fly   257 CVSILRKLMHVGN-----CTYEKRFICQY 280
            ||.::..    |.     |.....|:|::
Human   256 CVEMVAS----GGWNDVACHTTMYFMCEF 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24A	NP_652637.1	CLECT	169..280	CDD:153057	31/117 (26%)
COLEC11	NP_001242914.1	Collagen	58..111	CDD:189968
COLEC11	NP_001242914.1	CLECT_collectin_like	165..280	CDD:153061	33/123 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	72	1.000	Inparanoid score	I5300
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.960