DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-24A and CLEC17A

DIOPT Version :9

Sequence 1:	NP_652637.1	Gene:	lectin-24A / 53543	FlyBaseID:	FBgn0040104	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_001191047.1	Gene:	CLEC17A / 388512	HGNCID:	34520	Length:	378	Species:	Homo sapiens

Alignment Length:	233	Identity:	43/233 - (18%)
Similarity:	97/233 - (41%)	Gaps:	31/233 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 QDKWNTCTEILANEARKDQIQLNIQLDALKADVSNIKASQLSKDEKLDRMEREQFAMHESLETIN 117
            |.:|.....:|        :..::.|..|...|:.||..:|.  |:|..:..:|.....::..:.
Human   166 QKRWMVYLCLL--------VVTSLFLGCLGLTVTLIKYQELM--EELRMLSFQQMTWRTNMTGMA 220

  Fly   118 RYLTVKLDRTKLQLEAIKNTMDYMKAQMDGYFSAINGVQCLQPGFEKIGDRYFYIEEDVELNWLD 182
            ....:|.|..:::.:..::.:: :...:|     ...:.|.: |:.....:.:|.....: :|.:
Human   221 GLAGLKHDIARVRADTNQSLVE-LWGLLD-----CRRITCPE-GWLPFEGKCYYFSPSTK-SWDE 277

  Fly   183 AQAKCRRMGGHLASIKTKQEFDAIVEKLDDSKSYFLGVNENTKTGDFVSAASGKSCLYHEWGPGE 247
            |:..|:....||..|.:..|.:.:.:.....:.|:||:|:..:.||: ....|.......|.|.|
Human   278 ARMFCQENYSHLVIINSFAEHNFVAKAHGSPRVYWLGLNDRAQEGDW-RWLDGSPVTLSFWEPEE 341

  Fly   248 PHHNNDQERCVSILRKLMHVG------NCTYEKRFICQ 279
            |::.:|:: |.:     |:.|      :|.....:||:
Human   342 PNNIHDED-CAT-----MNKGGTWNDLSCYKTTYWICE 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24A	NP_652637.1	CLECT	169..280	CDD:153057	26/117 (22%)
CLEC17A	NP_001191047.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..119
CLEC17A	NP_001191047.1	CLECT_DC-SIGN_like	254..374	CDD:153060	28/129 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X29
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910