DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-24A and Sftpd

DIOPT Version :9

Sequence 1:	NP_652637.1	Gene:	lectin-24A / 53543	FlyBaseID:	FBgn0040104	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_037010.1	Gene:	Sftpd / 25350	RGDID:	3667	Length:	374	Species:	Rattus norvegicus

Alignment Length:	161	Identity:	49/161 - (30%)
Similarity:	78/161 - (48%)	Gaps:	25/161 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 QLEAIKNTMDYMKAQMDGYFSAINGVQCLQPGFEKIGDRYFYI---EEDVELNWLDAQAKCRRMG 191
            |:||:...:..::|....|..|     .|.|..:.:||:.|..   ||..|    ||:..||:.|
  Rat   229 QMEALNGKLQRLEAAFSRYKKA-----ALFPDGQSVGDKIFRAANSEEPFE----DAKEMCRQAG 284

  Fly   192 GHLASIKTKQEFDAIVEKL--DDSKSYFLGVNENTKTGDFVSAASGKSCLYHEWGPGEPHHNNDQ 254
            |.|||.::..| :|.|::|  ..||:.||.:.:....|.| :..:|::.:|..|.||||::|...
  Rat   285 GQLASPRSATE-NAAVQQLVTAHSKAAFLSMTDVGTEGKF-TYPTGEALVYSNWAPGEPNNNGGA 347

  Fly   255 ERCVSILRKLMHVGN-----CTYEKRFICQY 280
            |.||.|...    |.     |..::..||::
  Rat   348 ENCVEIFTN----GQWNDKACGEQRLVICEF 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24A	NP_652637.1	CLECT	169..280	CDD:153057	39/120 (33%)
Sftpd	NP_037010.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..221
		Collagen	41..89	CDD:189968
		Collagen	66..124	CDD:189968
		Collagen	114..172	CDD:189968
		Surfac_D-trimer	223..268	CDD:286141	11/43 (26%)
		CLECT	261..374	CDD:295302	40/122 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I11575
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	76	1.000	Inparanoid score	I5161
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960