DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-24A and FCER2

DIOPT Version :9

Sequence 1:	NP_652637.1	Gene:	lectin-24A / 53543	FlyBaseID:	FBgn0040104	Length:	282	Species:	Drosophila melanogaster
Sequence 2:	NP_001207429.1	Gene:	FCER2 / 2208	HGNCID:	3612	Length:	321	Species:	Homo sapiens

Alignment Length:	209	Identity:	50/209 - (23%)
Similarity:	91/209 - (43%)	Gaps:	53/209 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 EILANEAR-KDQ-IQLNIQLDALKADVSNIKASQLS-KDEKLDRMEREQFAMHESLETINRYLTV 122
            |:.|.:.| |.| ::|:..|:.|:||:|:.|:.:|: ::|..|.:||                 :
Human    94 ELRAEQQRLKSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLER-----------------L 141

  Fly   123 KLDRTKLQLEA------IKNTMDYMKAQMDGYFSAINGVQCLQP--GFEKIGDRYFYIEEDVELN 179
            :.:.|||::|.      :.||                   |.:.  .|::   :.:|..:..: .
Human   142 REEVTKLRMELQVSSGFVCNT-------------------CPEKWINFQR---KCYYFGKGTK-Q 183

  Fly   180 WLDAQAKCRRMGGHLASIKTKQEFDAIVEKLDDSKSYFLGVNENTKTGDFVSAASGKSCLYHEWG 244
            |:.|:..|..|.|.|.||.:.:|.|.:.:....:.|: :|:......|:|: ...|....|..|.
Human   184 WVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSW-IGLRNLDLKGEFI-WVDGSHVDYSNWA 246

  Fly   245 PGEPHHNNDQERCV 258
            ||||...:..|.||
Human   247 PGEPTSRSQGEDCV 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24A	NP_652637.1	CLECT	169..280	CDD:153057	25/90 (28%)
FCER2	NP_001207429.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..85
		Repetitive region	69..89
		RILP-like	<77..153	CDD:304877	21/75 (28%)
		Repetitive region	90..110		5/15 (33%)
		Repetitive region	111..131		7/19 (37%)
		CLECT	163..282	CDD:214480	27/104 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..321
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010