Protein Alignment lectin-24A and CLEC10A

DIOPT Version :10

• Sequence 1: NP_652637.1
• Gene: lectin-24A / 53543
• FlyBaseID: FBgn0040104
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: XP_011521915.1
• Gene: CLEC10A / 10462
• HGNCID: 16916
• Length: 319
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 62/325 - (19%)
• Similarity: 113/325 - (34%)
• Gaps: 93/325 - (28%)

  Fly    24 KIEIQ-----PLP------ALCNGYC--------------------FPTLKPVMEYVAIHQD--- 54
            |:::|     |||      .||:|.|                    |...|...:.|.:..|
Human    14 KVKVQGFKNGPLPLQSLLQRLCSGPCHLLLSLGLGLLLLVIICVVGFQNSKFQRDLVTLRTDFSN 78

  Fly    55 -KWNTCTEILANEARKDQIQLNIQLDALKADVSNIKASQLSKDEKLDRMEREQ------------ 106
             ..||..||.|..::...::..|.  :|||:|...|..:.:...:|.....::
Human    79 FTSNTVAEIQALTSQGSSLEETIA--SLKAEVEGFKQERQAGVSELQEHTTQKAHLGHCPHCPSV 141

  Fly   107 -FAMHESLETINRYLTVKLDRTKLQLEAIKNTMDYMKAQMDGYFSAINGVQ----CLQPGFEKIG 166
             ..:|..:....:.|...|.:...|:..:.|..:  :|..:|....:|.|:    |
Human   142 CVPVHSEMLLRVQQLVQDLKKLTCQVATLNNNGE--EASTEGTCCPVNWVEHQDSC--------- 195

  Fly   167 DRYFYIEEDVELNWLDAQAKCRRMGGHLASIKTKQEFDAIVEKLDDSKSYFLGVNENT---KTGD 228
              |::....  ::|.:|:..|:....||..|.:::| ...|:|...|...::|:::..   |..|
Human   196 --YWFSHSG--MSWAEAEKYCQLKNAHLVVINSREE-QNFVQKYLGSAYTWMGLSDPEGAWKWVD 255

  Fly   229 FVSAASGKSCLYHEWGPGEP-----HHNNDQERCVSILRKLMHVGN------CTYEKRFICQYGI 282
            ....|:|    :..|.||:|     |.....|.|..     .|...      |.....::|:.|:
Human   256 GTDYATG----FQNWKPGQPDDWQGHGLGGGEDCAH-----FHPDGRWNDDVCQRPYHWVCEAGL 311

  Fly   283  282
            Human   312  311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24A	NP_652637.1	CLECT	169..280	CDD:153057	26/124 (21%)
CLEC10A	XP_011521915.1	Lectin_N	5..170	CDD:461106	29/157 (18%)
		CLECT_DC-SIGN_like	184..308	CDD:153060	28/146 (19%)