Protein Alignment lectin-24A and clec4d

DIOPT Version :10

• Sequence 1: NP_652637.1
• Gene: lectin-24A / 53543
• FlyBaseID: FBgn0040104
• Length: 282
• Species: Drosophila melanogaster
• Sequence 2: XP_017948241.1
• Gene: clec4d / 101731344
• XenbaseID: XB-GENE-29085291
• Length: 175
• Species: Xenopus tropicalis
• Alignment Length: 753
• Identity: 144/753 - (19%)
• Similarity: 277/753 - (36%)
• Gaps: 208/753 - (27%)

  Fly    82 IVEKLGLTP--LSMEVAVPRYFR------REREEQLNERKKFMDDILKKIGALDEEVVEEELSEL 138
            :|::...:|  :|.||.|.:..:      :..:|::.||.:..   |:::.||:||:.... .|:
 Frog     3 VVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVS---LERVSALEEELAAAN-QEI 63

  Fly   139 EAIR----IIQTHERARQGRLRAQFMKEL---KLLKEKGKPDSSRDKSTTGLNAAMKIQKTWRGY 196
            .|:|    .||....:.:|...::.::.:   :.:.||...:.|.| ||...:..:::|:    .
 Frog    64 VALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVHEKRLSNGSID-STDETSQIVELQE----L 123

  Fly   197 ATRRQTRRKKMEEMIL-----IGMVPAPVTSARTALDELEDLKQFRYKQQKTFQDDYERSLVRVK 256
            ..::.....:|:|.:.     :|.|.....:||..|.:.|::           ...|:|
 Frog   124 LEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEM-----------NTKYQR------ 171

  Fly   257 EEISVKQGAAMTEDIADEIRTWFKEY---QKRTGRLPDFPSEEAGGSRHLLSRQGTESEM-SRSS 317
               .:::..|..||:.:.|.|..|.|   |:.:..:.|...:             .|:|: ::.:
 Frog   172 ---DIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDK-------------LENELANKEA 220

  Fly   318 VLSSRESKLKGSGKEKLAQKKPGELSLEEGLDKAFKPMQSSF-----LPEIKSGI-EEYTEVWKG 376
            :|...|.|.:               .|:|.|:.|.:.:|.:.     |||:::.: :....:.|.
 Frog   221 ILRQMEEKNR---------------QLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKA 270

  Fly   377 KDESQNLRQTYYDDMIYEEKYADVEAELRRIVDEIMRQELELLQIALERDRGGKKLKKSSKKARR 441
                             ||::.::|..:|.:..::..:..|     |:|.|..:|:.:
 Frog   271 -----------------EERHGNIEERMRHLEGQLEEKNQE-----LQRARQREKMNE------- 306

  Fly   442 SGKKGKKKKDKDLTPDR-TTESLFEELVTNGIIKKYPETPIKSYVGDLSYAARSALNPSPGDVRQ 505
              :..|:..|   |.|| .|||  .|.:...:.::......|:.:...|...|..|..|..|..:
 Frog   307 --EHNKRLSD---TVDRLLTES--NERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKER 364

  Fly   506 LIKQYCILPLGSETIRNFGPCIKSLLIAGPKGSGKTSLVHAICTETGSVLFDISPPNIVGKYPGK 570
            |.::.       |.:|                    |.:..:...|||::....|..
 Frog   365 LAEEI-------EKLR--------------------SELDQLKMRTGSLIEPTIPRT-------- 394

  Fly   571 SGLIMLMHLISKVSRLLQPSVIYFGDAEKPF-MKKIPKTDRTDPKRLKKDLPKLVKNIQPED--R 632
                   ||  ..|..|:.||....|::..: ..|:.:..|.....:::|.|| ||::...:  |
 Frog   395 -------HL--DTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEPK-VKSLGDHEWNR 449

  Fly   633 IMLIGT-SDCPWEGDMKLMVQTYQRFIYIPRPDYGALSFAWKELLSHYSGVHRQFDTGAMAKISD 696
            ...||. |..|:|.|.::.        .|...|...: |:..:|||. || |....|.||.....
 Frog   450 TQQIGVLSSHPFESDTEMS--------DIDDDDRETI-FSSMDLLSP-SG-HSDAQTLAMMLQEQ 503

  Fly   697 GYTIGSVVRCIRE-----------------VITCKRMLQLRVHPLTHLELINALSALEPVYKEEE 744
            ...|...:|.|:|                 .::.:.:...||||.|.:......|:|........
 Frog   504 LDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSG 568

  Fly   745 EAFLYWWCKTPLGRRRSKQMEKDHEAMMEMENVPKKKK 782
            .:       ||....||...|.|...:|.:.:..:|.:
 Frog   569 HS-------TPKLTPRSPAREMDRMGVMTLPSDLRKHR 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lectin-24A	NP_652637.1	CLECT	169..280	CDD:153057	21/115 (18%)
clec4d	XP_017948241.1	CLECT_DC-SIGN_like	52..174	CDD:153060	26/147 (18%)