DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-28C and COLEC11

DIOPT Version :9

Sequence 1:	NP_001285727.1	Gene:	lectin-28C / 53542	FlyBaseID:	FBgn0040099	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001242914.1	Gene:	COLEC11 / 78989	HGNCID:	17213	Length:	285	Species:	Homo sapiens

Alignment Length:	160	Identity:	42/160 - (26%)
Similarity:	76/160 - (47%)	Gaps:	13/160 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 KMEGQLSDLQEALTSITTSLKNMSAKINILHRFKRIGSR-YLHIEDIVQQNWTSALSACQKMGGN 174
            |..|::.:....|||....:||..|.:      :...|: ||.:::  ::.:..|..:||..||.
Human   134 KAIGEMDNQVSQLTSELKFIKNAVAGV------RETESKIYLLVKE--EKRYADAQLSCQGRGGT 190

  Fly   175 LASIINEADFNAIVSQLSKDN--TYMIGISDLAEKGVFISVSSGKRAPFLKWNPGEPLYEHVDQR 237
            |:...:||....:.:.|::..  ...|||:||.::|.|:.........|.||..|||...:.::.
Human   191 LSMPKDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEED 255

  Fly   238 CVSIHNGGMW-VASCTSDFKYICEAN-ENV 265
            ||.:...|.| ..:|.:...::||.: ||:
Human   256 CVEMVASGGWNDVACHTTMYFMCEFDKENM 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-28C	NP_001285727.1	Mer2	<12..134	CDD:286200	7/22 (32%)
lectin-28C	NP_001285727.1	CLECT	160..260	CDD:153057	27/102 (26%)
COLEC11	NP_001242914.1	Collagen	58..111	CDD:189968
COLEC11	NP_001242914.1	CLECT_collectin_like	165..280	CDD:153061	31/116 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	72	1.000	Inparanoid score	I5300
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.960