DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-28C and SFTPA1

DIOPT Version :9

Sequence 1:	NP_001285727.1	Gene:	lectin-28C / 53542	FlyBaseID:	FBgn0040099	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001087239.2	Gene:	SFTPA1 / 653509	HGNCID:	10798	Length:	263	Species:	Homo sapiens

Alignment Length:	199	Identity:	45/199 - (22%)
Similarity:	68/199 - (34%)	Gaps:	63/199 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 QEIQAQQRDIEKEIESQKTSLTESWKKIIAEDIENRTNRSELKMEGQLSDLQEAL-----TSITT 128
            :|:||...|...:|                     ...|..|.::|.:..:.|.:     .|||.
Human   120 EELQATLHDFRHQI---------------------LQTRGALSLQGSIMTVGEKVFSSNGQSITF 163

  Fly   129 SLKNMSAKINILHRFKRIGSRYLHIEDIVQQNWTSALSACQKMGGNLASIINEADFNAIVSQLSK 193
                                      |.:|:       ||.:.||.:|...|..:..||.|.:.|
Human   164 --------------------------DAIQE-------ACARAGGRIAVPRNPEENEAIASFVKK 195

  Fly   194 DNTY-MIGISDLAEKGVFISVSSGKRAPFLKWNPGEPLYEHVDQRCVSIHNGGMW-VASCTSDFK 256
            .||| .:|:::....|.| ..|.|....:..|..|||.....:| ||.::..|.| ..:|.....
Human   196 YNTYAYVGLTEGPSPGDF-RYSDGTPVNYTNWYRGEPAGRGKEQ-CVEMYTDGQWNDRNCLYSRL 258

  Fly   257 YICE 260
            .|||
Human   259 TICE 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-28C	NP_001285727.1	Mer2	<12..134	CDD:286200	12/69 (17%)
lectin-28C	NP_001285727.1	CLECT	160..260	CDD:153057	29/101 (29%)
SFTPA1	NP_001087239.2	Collagen	43..115	CDD:189968
SFTPA1	NP_001087239.2	CLECT_collectin_like	151..263	CDD:153061	37/147 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	72	1.000	Inparanoid score	I5300
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8166
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.080