DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lectin-28C and hbl2

DIOPT Version :9

Sequence 1:	NP_001285727.1	Gene:	lectin-28C / 53542	FlyBaseID:	FBgn0040099	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_009296949.2	Gene:	hbl2 / 566971	ZFINID:	ZDB-GENE-070912-286	Length:	253	Species:	Danio rerio

Alignment Length:	153	Identity:	42/153 - (27%)
Similarity:	72/153 - (47%)	Gaps:	15/153 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 QEALTSITTSLKNMSAKINILHR------FKRIGSRYLHIEDIVQQNWTSALSACQKMGGNLASI 178
            :..:.|:.:.::|:.|:|:.:.:      |:|:|.:| ::.|.:..|:...:..|:..||.|...
Zfish   101 ESVIESLKSEIQNLKAEIDTIEKAASFSNFRRVGQKY-YVTDGILGNFNDGIKFCKDAGGTLVVP 164

  Fly   179 INEADFNAIV-----SQLSKDNTYMIGISDLAEKGVFISVSSGKRAPFLKWNPGEPLYEHVDQRC 238
            ...|:..|:|     |.||....| ||::|...:|.|:.: .||:..|..|.||:|......|.|
Zfish   165 KTAAENQALVRVSVSSALSTGKPY-IGVTDRETEGQFVDI-EGKQLTFTNWGPGQPDDYRGGQDC 227

  Fly   239 VSIHNGGMWVASCTSDFK-YICE 260
            ..|...|.|......|.: .|||
Zfish   228 GVIEVSGTWDDGNCGDIRPIICE 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-28C	NP_001285727.1	Mer2	<12..134	CDD:286200	2/13 (15%)
lectin-28C	NP_001285727.1	CLECT	160..260	CDD:153057	31/105 (30%)
hbl2	XP_009296949.2	Collagen	<36..70	CDD:189968
hbl2	XP_009296949.2	CLECT_collectin_like	135..251	CDD:153061	35/119 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	76	1.000	Inparanoid score	I5252
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8166
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.990