DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-28C and MBL2

DIOPT Version :9

Sequence 1:	NP_001285727.1	Gene:	lectin-28C / 53542	FlyBaseID:	FBgn0040099	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_000233.1	Gene:	MBL2 / 4153	HGNCID:	6922	Length:	248	Species:	Homo sapiens

Alignment Length:	119	Identity:	34/119 - (28%)
Similarity:	60/119 - (50%)	Gaps:	7/119 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 KRIGSR-YLHIEDIVQQNWTSALSACQKMGGNLASIINEADFNAIVSQLSKDNTYMIGISDLAEK 207
            |::|:: :|...:|:......||  |.|...::|:..|.|: |..:..|.|:..: :||:|...:
Human   132 KQVGNKFFLTNGEIMTFEKVKAL--CVKFQASVATPRNAAE-NGAIQNLIKEEAF-LGITDEKTE 192

  Fly   208 GVFISVSSGKRAPFLKWNPGEPLYEHVDQRCVSIHNGGMW-VASCTSDFKYICE 260
            |.|:.: :|.|..:..||.|||.....|:.||.:...|.| ...|::....:||
Human   193 GQFVDL-TGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSHLAVCE 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-28C	NP_001285727.1	Mer2	<12..134	CDD:286200
lectin-28C	NP_001285727.1	CLECT	160..260	CDD:153057	28/100 (28%)
MBL2	NP_000233.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	43..113
MBL2	NP_000233.1	CLECT_collectin_like	136..246	CDD:153061	32/115 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11773
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	72	1.000	Inparanoid score	I5300
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.960