DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-28C and Mbl1

DIOPT Version :9

Sequence 1:	NP_001285727.1	Gene:	lectin-28C / 53542	FlyBaseID:	FBgn0040099	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_036731.2	Gene:	Mbl1 / 24548	RGDID:	3055	Length:	238	Species:	Rattus norvegicus

Alignment Length:	162	Identity:	42/162 - (25%)
Similarity:	78/162 - (48%)	Gaps:	19/162 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 EGQLSDLQEALTSITTSLKNMSAKINI----------LHRF---KRIGSRYLHIEDIVQQNWTSA 164
            :||..|..:: .:|...|.||.|:||.          ||.|   |:.|.::. :.:..:..::..
  Rat    79 KGQKGDRGDS-RAIEVKLANMEAEINTLKSKLELTNKLHAFSMGKKSGKKFF-VTNHERMPFSKV 141

  Fly   165 LSACQKMGGNLASIINEADFNAIVSQLSKDNTYMIGISDLAEKGVFISVSSGKRAPFLKWNPGEP 229
            .:.|.::.|.:| |...|:.|..:.:::|.:.: :||:|...:|.|:.|:.| |..:..|...||
  Rat   142 KALCSELRGTVA-IPRNAEENKAIQEVAKTSAF-LGITDEVTEGQFMYVTGG-RLTYSNWKKDEP 203

  Fly   230 LYEHVDQRCVSIHNGGMW-VASCTSDFKYICE 260
            ......:.||:|.:.|:| ..||.:....:||
  Rat   204 NDHGSGEDCVTIVDNGLWNDISCQASHTAVCE 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-28C	NP_001285727.1	Mer2	<12..134	CDD:286200	6/20 (30%)
lectin-28C	NP_001285727.1	CLECT	160..260	CDD:153057	25/100 (25%)
Mbl1	NP_036731.2	Collagen	36..>88	CDD:189968	3/8 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..87		3/7 (43%)
		CLECT_collectin_like	126..236	CDD:153061	27/114 (24%)
		Calcium-dependent carbohydrate binding. /evidence=ECO:0000269\|PubMed:11850428, ECO:0000269\|PubMed:1436090, ECO:0000269\|PubMed:9033386	202..210		2/7 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I11575
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910