DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-28C and Asgr2

DIOPT Version :9

Sequence 1:	NP_001285727.1	Gene:	lectin-28C / 53542	FlyBaseID:	FBgn0040099	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001300854.1	Gene:	Asgr2 / 11890	MGIID:	88082	Length:	301	Species:	Mus musculus

Alignment Length:	273	Identity:	56/273 - (20%)
Similarity:	97/273 - (35%)	Gaps:	67/273 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 PRNQCGPFCLEALMPLIGHI-------------AQHQEQWKTCK----------LQEIQAQQRDI 78
            |:..|..|.| :|:.|..:|             .|.||:::|.|          |.|..|..
Mouse    50 PQRLCSTFRL-SLLALAFNILLLVVICVVSSQSIQLQEEFRTLKETFSNFSSSTLMEFGALD--- 110

  Fly    79 EKEIESQKTSLTESWKKIIAEDIENRTNRSELKMEGQLSDLQEALTSITTSLKNMSAKINILH-- 141
              .:.....::..||...:.|      .:.:||.:.  |.|...|......|:.::.::....
Mouse   111 --TLGGSTNAILTSWLAQLEE------KQQQLKADH--STLLFHLKHFPMDLRTLTCQLAYFQSN 165

  Fly   142 ----------RFKRIGSRYLHIEDIVQQNWTSALSACQKMGGNLASIIN---EADFNAIVSQLSK 193
                      .|.  ||.|....|.:  .|..|...||....:|. :||   |.||  :|...|:
Mouse   166 GTECCPVNWVEFG--GSCYWFSRDGL--TWAEADQYCQLENAHLL-VINSREEQDF--VVKHRSQ 223

  Fly   194 DNTYMIGISDLAEKGVFISVSSGKRAPFLKWNPGEP--LYEHVD---QRCVSIHNGGMWVAS-CT 252
            .:.: ||::|......::. .:..|:.:..|...:|  ...|..   :.|..|.:.|.|..: |.
Mouse   224 FHIW-IGLTDRDGSWKWVD-GTDYRSNYRNWAFTQPDNWQGHEQGGGEDCAEILSDGHWNDNFCQ 286

  Fly   253 SDFKYICEANENV 265
            ...:::||...|:
Mouse   287 QVNRWVCEKRRNI 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-28C	NP_001285727.1	Mer2	<12..134	CDD:286200	24/119 (20%)
lectin-28C	NP_001285727.1	CLECT	160..260	CDD:153057	24/108 (22%)
Asgr2	NP_001300854.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43
		Lectin_N	29..162	CDD:281887	24/125 (19%)
		CLECT_DC-SIGN_like	170..295	CDD:153060	30/133 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910