DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-28C and COLEC10

DIOPT Version :9

Sequence 1:	NP_001285727.1	Gene:	lectin-28C / 53542	FlyBaseID:	FBgn0040099	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_006429.2	Gene:	COLEC10 / 10584	HGNCID:	2220	Length:	277	Species:	Homo sapiens

Alignment Length:	157	Identity:	43/157 - (27%)
Similarity:	75/157 - (47%)	Gaps:	18/157 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 KMEGQLSDLQEALTSITTSLKNMSAKINILHRFKRIGSRYLHIEDIVQQ--NWTSALSACQKMGG 173
            |..||| |:  ::..:.||:|.:.   |::...:....::.:   |||:  |:..:|:.|:..||
Human   126 KFVGQL-DI--SIARLKTSMKFVK---NVIAGIRETEEKFYY---IVQEEKNYRESLTHCRIRGG 181

  Fly   174 NLASIINEADFNAIVSQLSKDNTY--MIGISDLAEKGVFISVSSGKRAPFLKWNPGEPL--YEHV 234
            .||...:||....|...::|...:  .||::||..:|.::...:.....:..||.|||.  |.|.
Human   182 MLAMPKDEAANTLIADYVAKSGFFRVFIGVNDLEREGQYMFTDNTPLQNYSNWNEGEPSDPYGHE 246

  Fly   235 DQRCVSIHNGGMW-VASCTSDFKYICE 260
            |  ||.:.:.|.| ...|.....::||
Human   247 D--CVEMLSSGRWNDTECHLTMYFVCE 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-28C	NP_001285727.1	Mer2	<12..134	CDD:286200	8/22 (36%)
lectin-28C	NP_001285727.1	CLECT	160..260	CDD:153057	29/104 (28%)
COLEC10	NP_006429.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..107
		Collagen	45..111	CDD:189968
		CLECT_collectin_like	157..272	CDD:153061	34/120 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	72	1.000	Inparanoid score	I5300
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100086
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.860