DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-28C and CLEC3A

DIOPT Version :9

Sequence 1:	NP_001285727.1	Gene:	lectin-28C / 53542	FlyBaseID:	FBgn0040099	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_005743.5	Gene:	CLEC3A / 10143	HGNCID:	2052	Length:	197	Species:	Homo sapiens

Alignment Length:	184	Identity:	48/184 - (26%)
Similarity:	75/184 - (40%)	Gaps:	18/184 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 QKTSLTESWKKIIAEDIENRTNRSELKMEGQLSDLQEALTSITTSLKNMSAKINILHRFKRIGSR 149
            |.||.|...|      ....:.|.....:|.|....|.|.:...:||.:.|...:..|..::..:
Human    19 QTTSHTSRLK------ARKHSKRRVRDKDGDLKTQIEKLWTEVNALKEIQALQTVCLRGTKVHKK 77

  Fly   150 -YLHIEDIVQQNWTSALSACQKMGGNLASIINEADFNAIVS----QLSKDNTYMIGISDLAEKGV 209
             ||..|.:  :::..|...|...||.|....|..:.||:..    .|...|.:.:||:|:..:|.
Human    78 CYLASEGL--KHFHEANEDCISKGGILVIPRNSDEINALQDYGKRSLPGVNDFWLGINDMVTEGK 140

  Fly   210 FISVSSGKRAPFLKWNPGEPLYEHVDQRCVSIHNG--GMWV-ASCTSDFKYICE 260
            |:.| :|....||.|:..:| .....:.||.....  |.|. .:|.|..:||||
Human   141 FVDV-NGIAISFLNWDRAQP-NGGKRENCVLFSQSAQGKWSDEACRSSKRYICE 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-28C	NP_001285727.1	Mer2	<12..134	CDD:286200	12/48 (25%)
lectin-28C	NP_001285727.1	CLECT	160..260	CDD:153057	29/106 (27%)
CLEC3A	NP_005743.5	CLECT_tetranectin_like	68..193	CDD:153066	35/129 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11773
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910