DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-28C and mrc1

DIOPT Version :9

Sequence 1:	NP_001285727.1	Gene:	lectin-28C / 53542	FlyBaseID:	FBgn0040099	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_012821081.2	Gene:	mrc1 / 100493504	XenbaseID:	XB-GENE-494275	Length:	1450	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	63/258 - (24%)
Similarity:	102/258 - (39%)	Gaps:	74/258 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 EQWKTCKLQEIQAQQRDIEKE--------------------IESQKT----SLTESWK----KII 97
            |.|:.||.::  ::...|..|                    :.|.||    ..|::||    |..
Frog  1114 EAWRKCKSED--SELVSITDEYTNSFLRVYTSKYREPFWIGLNSNKTGNQYKWTDNWKLRYTKWA 1176

  Fly    98 AEDIENRTNRSELKMEGQ--LSDLQEALTSITTSLKNMSA-------------------KINILH 141
            ||:.:..|....:.::||  .|...|...||   .|...|                   :..|..
Frog  1177 AEEPKKTTACVYMDIDGQWKTSSCTENYFSI---CKQSDAIAPTDPPQKPGKCPPDSDDRSWIPF 1238

  Fly   142 RFKRIGSRYLHIEDIVQQNWTSALSACQKMGGNLASIINEADFNAIVSQL----SKDNTYMIGI- 201
            |    |..|| |:....:||..|...|.:.||:|||..:..:.|.:..|:    .:..::.||:
Frog  1239 R----GHCYL-IQVSYTKNWYQASLECLRFGGSLASFDDSLESNFVWHQIERLEDRVKSFWIGMY 1298

  Fly   202 SDLAEKGVFISVSSGKRAP--FLKWNPGEPLYEHVDQRCVSIHNG-GMW-VASCTSDFKYICE 260
            .::..|.:::.     .||  |:.||.||| .:|.|:.||.:::. |.| ...|:|...|||:
Frog  1299 QNVENKWLWLD-----NAPVDFVNWNIGEP-SDHNDEHCVEMYSSHGTWNNLYCSSYRGYICK 1355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-28C	NP_001285727.1	Mer2	<12..134	CDD:286200	23/102 (23%)
lectin-28C	NP_001285727.1	CLECT	160..260	CDD:153057	32/108 (30%)
mrc1	XP_012821081.2	RICIN	26..140	CDD:214672
		FN2	159..207	CDD:128373
		CLECT	227..339	CDD:153057
		CLECT	359..483	CDD:214480
		CLECT	501..623	CDD:214480
		CLECT	643..775	CDD:413318
		CLECT	799..920	CDD:214480
		CLECT	941..1076	CDD:214480
		CLECT	1095..1209	CDD:214480	22/99 (22%)
		CLECT	1226..1355	CDD:214480	38/139 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910