DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-46Ca and mrc1b

DIOPT Version :9

Sequence 1:	NP_652633.1	Gene:	lectin-46Ca / 53523	FlyBaseID:	FBgn0040093	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_001297773.1	Gene:	mrc1b / 559502	ZFINID:	ZDB-GENE-070705-13	Length:	1428	Species:	Danio rerio

Alignment Length:	326	Identity:	69/326 - (21%)
Similarity:	123/326 - (37%)	Gaps:	71/326 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EKDKGPCGKPYLRELNGKCFYVGIKKINWFGAQNNCLRKGLNLADVSTMEDFKAVVHYVTSQVGF 90
            |...|.|..|::.. :|.|:::...|..|..|::.|||:|.:|..:.:.|:    ..:..:|:|:
Zfish   344 EVTTGFCQSPWIPH-SGNCYFLHRTKQTWLEARDICLREGGDLLSILSTEE----QSFAITQLGY 403

  Fly    91 ---DDFWFGGNDLQSEGRFKYISSGKLVRYMGDSNIVEPTQRS-NLDDCLEIRIRPNVTVVLDVN 151
               |..|.|.||.:::..|::.....:.  .....:.|||..: :.:||  :.:|.......|..
Zfish   404 SKTDQLWIGFNDRKTQMLFEWSDQSSVP--FASWEVGEPTHSAQHAEDC--VLMRGEEGKWADDV 464

  Fly   152 CQEKKYFICEQNQMKCAVPAED-----SGDGQKHSHEHLHHFHHDAGQKDKQETGIKEQSVESDS 211
            |::|..|||::   |.:..|.:     :..|.|.......::.:.||.:.|.....|:...:::|
Zfish   465 CEKKYGFICKR---KTSTKASNNDTVVANPGCKKGWIRYGYYCYMAGSETKTSEEAKQTCEKAES 526

  Fly   212 RPADNSNSTE-----------------IGVSKEKEAEGAPTPGDGGGTTEPVFENGMENAAE-PI 258
            |..|.|:..|                 ||:|.:|:..              .||  ..|..: |.
Zfish   527 RLVDVSSRVENAFLVNLVGARPEKYFWIGLSNQKDVH--------------TFE--WTNTKQVPF 575

  Fly   259 AEQEQTVPPGGTGPPAAADATGAATPAPDAAA------------AEGATPAAAPPAEGAPAAEAA 311
            ......:|  |......|..||......|..:            |:.....||||.  .|:.:..
Zfish   576 THFNSGMP--GRKQGCVAMTTGIVAGLWDVLSCSNKEKYICKQRADALVTTAAPPT--TPSLDCP 636

  Fly   312 T 312
            |
Zfish   637 T 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-46Ca	NP_652633.1	CLECT	43..162	CDD:153057	30/122 (25%)
mrc1b	NP_001297773.1	RICIN	25..>117	CDD:238092
		fn2	163..204	CDD:278469
		CLECT	227..334	CDD:153057
		CLECT	350..474	CDD:214480	32/132 (24%)
		CLECT	493..615	CDD:214480	24/139 (17%)
		CLECT	648..764	CDD:153057
		CLECT	785..905	CDD:214480
		CLECT	926..1062	CDD:214480
		CLECT	1089..1196	CDD:153057
		CLECT	1223..1347	CDD:214480
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BNTX
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810