DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-46Ca and Clec4a

DIOPT Version :9

Sequence 1:	NP_652633.1	Gene:	lectin-46Ca / 53523	FlyBaseID:	FBgn0040093	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_001005899.2	Gene:	Clec4a / 474143	RGDID:	1359662	Length:	240	Species:	Rattus norvegicus

Alignment Length:	148	Identity:	27/148 - (18%)
Similarity:	61/148 - (41%)	Gaps:	14/148 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KEKDKGPCGKPYLRELNGKCFYV-----GIKKINWFGAQNNCLRKGLNLADVSTMEDFKAVVHYV 84
            :||....|.|.: :.....|::|     ...|.:|..::.||...|.:|..:.:.|:    ..::
  Rat   100 EEKSWSCCPKNW-KPFGSHCYWVTKHTSTYSKASWNESEKNCFSMGAHLLVIHSKEE----QDFI 159

  Fly    85 TSQVGFDDFWFGGNDLQSEGRFKYISSGKLVRYMGDSNIVEPTQRSNLDD-CLEIRIRPNVTVVL 148
            |..:..|..:|.|.......:::::|.   ..|...:......:.|:.|: |:.|....:.....
  Rat   160 TGILNRDAAYFIGLWDSGHRQWQWVSQ---TPYNASATFWHKGEPSSDDEKCVIINHLNSGWGWN 221

  Fly   149 DVNCQEKKYFICEQNQMK 166
            |:.|..|:..:|:..:::
  Rat   222 DIPCSGKQQSVCQMKKIQ 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-46Ca	NP_652633.1	CLECT	43..162	CDD:153057	23/124 (19%)
Clec4a	NP_001005899.2	ITIM motif	5..10
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	18..38
		CLECT_DC-SIGN_like	107..235	CDD:153060	25/135 (19%)
		Mannose binding. /evidence=ECO:0000250\|UniProtKB:Q9UMR7	200..202		0/1 (0%)
		N-acetyl-D-glucosamine binding. /evidence=ECO:0000250\|UniProtKB:Q9UMR7	211..213		1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344274
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940