DRSC/TRiP Functional Genomics Resources

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Protein Alignment lectin-46Ca and VCAN

DIOPT Version :10

Sequence 1:NP_652633.1 Gene:lectin-46Ca / 53523 FlyBaseID:FBgn0040093 Length:328 Species:Drosophila melanogaster
Sequence 2:NP_004376.2 Gene:VCAN / 1462 HGNCID:2464 Length:3396 Species:Homo sapiens


Alignment Length:157 Identity:33/157 - (21%)
Similarity:61/157 - (38%) Gaps:32/157 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 EKDKGPCGKPYLRELNGKCFYVGIKKINWFGAQNNCLRKGLNLADVSTMEDFKAVVHYVTSQVGF 90
            |:|...|...: .:..|:|:.....:..|..|:..|..:|.:|..:.:.|:     ....::||.
Human  3163 EQDTETCDYGW-HKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEE-----QMFVNRVGH 3221

  Fly    91 DDFWFGGNDLQSEGRFKYISSGKLVRYMGDSNIVEPTQRSNL----DDCLEIRIRPNVTVVL--- 148
            |..|.|.||...|..|:: :.|..::|..    ..|.|..:.    :||:         |::   
Human  3222 DYQWIGLNDKMFEHDFRW-TDGSTLQYEN----WRPNQPDSFFSAGEDCV---------VIIWHE 3272

  Fly   149 -----DVNCQEKKYFICEQNQMKCAVP 170
                 ||.|.....:.|::..:.|..|
Human  3273 NGQWNDVPCNYHLTYTCKKGTVACGQP 3299

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lectin-46CaNP_652633.1 CLECT 43..162 CDD:153057 27/130 (21%)
VCANNP_004376.2 Ig_Versican 26..152 CDD:409482
Ig strand A 26..29 CDD:409482
Ig strand A' 32..34 CDD:409482
Ig strand B 38..46 CDD:409482
Ig strand C 63..69 CDD:409482
Ig strand C' 80..83 CDD:409482
Ig strand D 101..106 CDD:409482
Ig strand E 112..118 CDD:409482
Ig strand F 126..133 CDD:409482
Ig strand G 143..152 CDD:409482
Link_domain_CSPGs_modules_1_3 150..244 CDD:239594
Link_domain_CSPGs_modules_2_4 251..346 CDD:239597
GAG-alpha (glucosaminoglycan attachment domain) 348..1335
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 420..439
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 603..622
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 807..829
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1126..1154
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1277..1316
GAG-beta 1336..3089
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1420..1497
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1510..1539
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1717..1737
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1759..1789
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1962..1994
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2107..2134
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2168..2188
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2371..2396
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2445..2473
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2493..2518
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2598..2617
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2834..2856
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2881..2905
EGF_CA 3091..3125 CDD:238011
EGF_CA 3127..3163 CDD:238011 33/157 (21%)
CLECT_CSPGs 3169..3292 CDD:153058 29/142 (20%)
CCP 3296..3352 CDD:153056 2/4 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 3371..3396
Blue background indicates that the domain is not in the aligned region.

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