DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-46Ca and CLEC10A

DIOPT Version :9

Sequence 1:	NP_652633.1	Gene:	lectin-46Ca / 53523	FlyBaseID:	FBgn0040093	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	XP_011521915.1	Gene:	CLEC10A / 10462	HGNCID:	16916	Length:	319	Species:	Homo sapiens

Alignment Length:	164	Identity:	34/164 - (20%)
Similarity:	60/164 - (36%)	Gaps:	32/164 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KGPCGKPYLRELNGKCFYVGIKKINWFGAQNNCLRKGLNLADVSTMEDFKAVVHYVTSQVGFDDF 93
            :|.|......|....|::.....::|..|:..|..|..:|..:::.|:    .::|...:|....
Human   180 EGTCCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREE----QNFVQKYLGSAYT 240

  Fly    94 WFGGNDLQSEGRFKYISSGKLVRYMGDSNIVEPTQRSNL--------DDCLEIRIRPNVTVVLDV 150
            |.|.:|  .||.:|::..   ..|.......:|.|..:.        :||  ....|:.....||
Human   241 WMGLSD--PEGAWKWVDG---TDYATGFQNWKPGQPDDWQGHGLGGGEDC--AHFHPDGRWNDDV 298

  Fly   151 NCQEKKYFICEQNQMKCAVPAEDSGDGQKHSHEH 184
             ||...:::||            :|.||.....|
Human   299 -CQRPYHWVCE------------AGLGQTSQESH 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-46Ca	NP_652633.1	CLECT	43..162	CDD:153057	26/126 (21%)
CLEC10A	XP_011521915.1	Lectin_N	18..170	CDD:281887
CLEC10A	XP_011521915.1	CLECT_DC-SIGN_like	184..308	CDD:153060	26/135 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150825
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840