DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-46Ca and CLEC4M

DIOPT Version :9

Sequence 1:	NP_652633.1	Gene:	lectin-46Ca / 53523	FlyBaseID:	FBgn0040093	Length:	328	Species:	Drosophila melanogaster
Sequence 2:	NP_055072.3	Gene:	CLEC4M / 10332	HGNCID:	13523	Length:	399	Species:	Homo sapiens

Alignment Length:	125	Identity:	30/125 - (24%)
Similarity:	50/125 - (40%)	Gaps:	14/125 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 GKCFYVGIKKINWFGAQNNCLRKGLNLADVSTMEDFKAVVHYVTSQVGFDDFWFGGNDLQSEGRF 106
            |.|:::...:.||..:...|......|..:.|.|:...:....:....|.  |.|.:||..||.:
Human   277 GNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFS--WMGLSDLNQEGTW 339

  Fly   107 KYISSGKL----VRYMGDSNIVEPTQRSNLDDCLEIRIRPNVTVVLDVNCQEKKYFICEQ 162
            :::....|    .||.   |..||....| :||.|.    :.:...|..|....|:||::
Human   340 QWVDGSPLSPSFQRYW---NSGEPNNSGN-EDCAEF----SGSGWNDNRCDVDNYWICKK 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-46Ca	NP_652633.1	CLECT	43..162	CDD:153057	29/122 (24%)
CLEC4M	NP_055072.3	Endocytosis signal. /evidence=ECO:0000250	14..15
		transmembrane domain	44..71
		7 X approximate tandem repeats	108..269
		DUF342	<140..251	CDD:302792
		CLECT_DC-SIGN_like	268..391	CDD:153060	30/123 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150809
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1509611at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.950