DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-33A and SFTPD

DIOPT Version :9

Sequence 1:	NP_001097145.1	Gene:	lectin-33A / 53516	FlyBaseID:	FBgn0040096	Length:	177	Species:	Drosophila melanogaster
Sequence 2:	NP_003010.4	Gene:	SFTPD / 6441	HGNCID:	10803	Length:	375	Species:	Homo sapiens

Alignment Length:	141	Identity:	34/141 - (24%)
Similarity:	50/141 - (35%)	Gaps:	40/141 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VGNKCYHVSLQEANWHVADRSCRKLGAEL--------------MVLDNQEDKLLTTTFLKSMGLS 81
            ||.|.:..:.....:..|...|.:.|.:|              :|:...|...|:.|..|:.| .
Human   260 VGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEG-K 323

  Fly    82 FTQSWHHSVWAGINCLGNRRTFLLARNGETVPYLNWVPLEPNNASPEEDCVGFANYNGAFGYHDI 146
            ||..                      .||::.|.||.|.|||:....||||.... ||.  ::|.
Human   324 FTYP----------------------TGESLVYSNWAPGEPNDDGGSEDCVEIFT-NGK--WNDR 363

  Fly   147 ECKVQFPYVCQ 157
            .|..:...||:
Human   364 ACGEKRLVVCE 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-33A	NP_001097145.1	CLECT	24..157	CDD:214480	33/139 (24%)
SFTPD	NP_003010.4	Collagen	46..98	CDD:189968
		Collagen	130..201	CDD:189968
		Surfac_D-trimer	224..269	CDD:286141	3/8 (38%)
		CLECT_collectin_like	262..375	CDD:153061	32/139 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910