DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-33A and ASGR1

DIOPT Version :9

Sequence 1:	NP_001097145.1	Gene:	lectin-33A / 53516	FlyBaseID:	FBgn0040096	Length:	177	Species:	Drosophila melanogaster
Sequence 2:	NP_001662.1	Gene:	ASGR1 / 432	HGNCID:	742	Length:	291	Species:	Homo sapiens

Alignment Length:	145	Identity:	36/145 - (24%)
Similarity:	61/145 - (42%)	Gaps:	27/145 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 CPLPFSRVGNKCYHVSLQEANWHVADRSCRKLGAELMVLDNQEDKLLTTTFLKSMGLSFTQSWHH 88
            ||:.:......||..|.....|..||..||...|.|:|:.:.|::            .|.|  ||
Human   154 CPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQ------------KFVQ--HH 204

  Fly    89 ----SVWAGINCLGNRRTFLLARNGETVPYLNWVPLEPNN-----ASPEEDCVGFANYNGAFGYH 144
                :.|.|::.......::...:.|| .:.||.|.:|::     ....|||..|.: :|.  ::
Human   205 IGPVNTWMGLHDQNGPWKWVDGTDYET-GFKNWRPEQPDDWYGHGLGGGEDCAHFTD-DGR--WN 265

  Fly   145 DIECKVQFPYVCQRE 159
            |..|:..:.:||:.|
Human   266 DDVCQRPYRWVCETE 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-33A	NP_001097145.1	CLECT	24..157	CDD:214480	34/141 (24%)
ASGR1	NP_001662.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
		Endocytosis signal. /evidence=ECO:0000255	5..8
		Lectin_N	17..144	CDD:309178
		CLECT_DC-SIGN_like	154..279	CDD:153060	35/142 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150820
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000024
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840