Protein Alignment Myo28B1 and XIA

DIOPT Version :10

• Sequence 1: NP_723294.1
• Gene: Myo28B1 / 53515
• FlyBaseID: FBgn0040299
• Length: 2122
• Species: Drosophila melanogaster
• Sequence 2: NP_171954.1
• Gene: XIA / 839480
• AraportID: AT1G04600
• Length: 1730
• Species: Arabidopsis thaliana
• Alignment Length: 1802
• Identity: 499/1802 - (27%)
• Similarity: 783/1802 - (43%)
• Gaps: 370/1802 - (20%)

  Fly    10 GEYVWVK-PQNTTSEFAVPFGARIVRTEKTQTLVCDDRNKQFWVPAGDVLKAMHITSQE------ 67
            |.:|||: |.:...:..|    ..|.:|:. |:.|..:..        |.|..::..::
plant    10 GSHVWVEDPDDAWIDGEV----EEVNSEEI-TVNCSGKTV--------VAKLNNVYPKDPEFPEL 61

  Fly    68 DVEDMITLGDLQEYTILRNLQNRYAKQLIYTYTGSMLVAINPYQILP-IYTNREIQLYRNKSLAE 131
            .|:||..|..|.|..:|.||:.||....||||||::|:|:||::.|| :|.:..::.|:..:..|
plant    62 GVDDMTKLAYLHEPGVLLNLKCRYNANEIYTYTGNILIAVNPFKRLPHLYGSETMKQYKGTAFGE 126

  Fly   132 LPPHIFAISDNAFQRLQRLKENQCVVISGESGAGKTESTKLILQYLAAISGKHS----WIEQQII 192
            |.||.||::|:|::::.....:|.:::|||||||||||||:::||||.:.|:..    .:|||::
plant   127 LSPHPFAVADSAYRKMINEGVSQAILVSGESGAGKTESTKMLMQYLAYMGGRAESEGRSVEQQVL 191

  Fly   193 EANPIMEAFGNAKTVRNDNSSRFGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDERNYHIF 257
            |:||::|||||||||||:|||||||::||:|..:|.|.||.|:.||||:||:...|..|||||.|
plant   192 ESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDQRGRISGAAIRTYLLERSRVCQVSDPERNYHCF 256

  Fly   258 YCMLAGLSTAERERLKLQEQSPSQYHYLAQGGCFTLPGRGDAKDFADIRAAMKVLSFKPEEVWSI 322
            | ||......|.||.||.:  ||.:.||.|..|:.|.|..|:|::...|.||.|:....||...|
plant   257 Y-MLCAAPEQETERYKLGK--PSTFRYLNQSNCYALDGLDDSKEYLATRKAMDVVGINSEEQDGI 318

  Fly   323 LSLLAAILHLGNLRFTATEVANLATAEIDDTP-NLQRVAQLLGIPISALNAALTQRTIFVHGEHV 386
            ..::||||||||:.|...|.:..:..:.:.:. :|:..|:|......||..:|.:|.:....|.:
plant   319 FRVVAAILHLGNIEFAKGEESEASEPKDEKSRFHLKVAAELFMCDGKALEDSLCKRVMVTRDESI 383

  Fly   387 TTSLSKEAAIEGRDAFVKSLYDGIFVRIVRRINETINKQVDQPMNS---IGVLDIFGFENFDNNS 448
            |.||..::|..||||..|.:|..:|..:|.:||.:|.    |..||   ||||||:|||:|..||
plant   384 TKSLDPDSAALGRDALAKIVYSKLFDWLVTKINNSIG----QDPNSKHIIGVLDIYGFESFKTNS 444

  Fly   449 FEQLCINYANENLQQFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMKPMNLMSLIDEE 513
            |||.|||..||.|||.|..|:|||||:||..|.|:|.:|||.|||.:||||..||..:::|:||.
plant   445 FEQFCINLTNEKLQQHFNQHVFKMEQEEYTKEEIDWSYIEFIDNQDVLDLIEKKPGGIIALLDEA 509

  Fly   514 SKFPKGTDQTLLEKLHVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPLGFLEKNRDSFSGDLR 578
            ..||:.|..|..:||:....|...:.|.|..||. |.|.||||.|.|....||:||:|...|:.:
plant   510 CMFPRSTHDTFAQKLYQTFKNHKRFGKPKLAQTD-FTICHYAGDVTYQTELFLDKNKDYVVGEHQ 573

  Fly   579 TLVQRSTNKYLVDIFPHEMPMDTAK--KQPTLCVKFRNSLDMLMRTLSQAHPYFIRCIKPNEYKE 641
            .|:..|...::..:|| .:|.:::|  |..::..:|:..|..|:.:||...|::|||:|||...:
plant   574 ALLSSSDCSFVSSLFP-PLPEESSKTSKFSSIGSQFKQQLQSLLESLSTTEPHYIRCVKPNNLLK 637

  Fly   642 PKNFDKELCVRQLRYSGMMETARIRRAGYPIRHAYRAFVERYRLLVPPV--GPLEQCD-CRKLAR 703
            |..|:....:.|||..|:||..||..||||.|..:..|:.|:|:|.|..  ...::.| |:||
plant   638 PDIFENINILHQLRCGGVMEAIRISCAGYPTRKPFNEFLTRFRILAPETTKSSYDEVDACKKL-- 700

  Fly   704 QICEVALPADSDRQYGKTKLFLRDEDDASLELQRSQLMLKSIVTIQRGIRRVLFRRYMKRYREAI 768
             :.:|.|   ...|.||||:|||....|.::..|::::..|...|||.:.....|:.....:.|.
plant   701 -LAKVDL---KGFQIGKTKVFLRAGQMAEMDAHRAEVLGHSARIIQRNVLTYQSRKKFLLLQAAS 761

  Fly   769 ITVQRYWRGRLQRRKYQVMRQGFHRL--------------------GAC-------IAAQQLTTK 806
            ..:|...||::.|..::.||:....|                    .||       ..|.::..:
plant   762 TEIQALCRGQVARVWFETMRREAASLRIQKQARTYICQNAYKTLCSSACSIQTGMRAKAARIELQ 826

  Fly   807 FTMVRCRTIKLQALSRGYLVRKDFQK--------------KLLERRKQNQLKKEELLKLAKMKEA 857
            ....|..||.:|:..|..|..:.:.:              |:..|..:|       ||:|    |
plant   827 LRKKRRATIIIQSQIRRCLCHQRYVRTKKAAITTQCGWRVKVARRELRN-------LKMA----A 880

  Fly   858 EELLRLQQLKEQKEREQREQQEKRLQEEQRLKAEAAARNALAMAAVQ--------QKRRTKPVKQ 914
            :|...||..|.:.| .|.|:....|:.|::::.|.....:..:.|:|        |.|.|:..|.
plant   881 KETGALQDAKTKLE-NQVEELTSNLELEKQMRMEIEEAKSQEIEALQSVLTDIKLQLRDTQETKS 944

  Fly   915 EAPKAPTLQARNSLPPPPTTLIVAAPLPTRPASAVTRINTIPE---------------SPG---T 961
            :  :...||          :::....|..|.... |:...|.:               |.|   |
plant   945 K--EISDLQ----------SVLTDIKLQLRDTQE-TKSKEISDLQSALQDMQLEIEELSKGLEMT 996

  Fly   962 IDVESSKQMVDDVFRFLNDEPDAALRKLNNISSGDTIRLPKSVPNNIDTSDFSYLKYAATYFGGG 1026
            .|:.:..:.:.:....|.::.|.:.||...||.....|:...|| .||.|....|
plant   997 NDLAAENEQLKESVSSLQNKIDESERKYEEISKISEERIKDEVP-VIDQSAIIKL---------- 1050

  Fly  1027 ATAQHERKPLKKSLLKHEHPIDEMASKAIWLTILRFMGDLPDVVSSPTLHVFDNENLMSDLASLL 1091
               :.|.:.||..:...|..|||:              |.....:||.:    .|.|..|:
plant  1051 ---ETENQKLKALVSSMEEKIDEL--------------DRKHDETSPNI----TEKLKEDV---- 1090

  Fly  1092 NTSDSYKPRLFVRQSQRRIPKPLASGEKEAQEFYQHWLNVPTSHLEKIHFIIGHGII-------- 1148
              |..|:....:.....|:...:.|.||:..|..    |..|...|:..:|:....:
plant  1091 --SFDYEIVSNLEAENERLKALVGSLEKKINESG----NNSTDEQEEGKYILKEESLTEDASIDN 1149

  Fly  1149 --------KNSLRDEILAQICKQL------YLNPSRSSYSRGWLLLSLCLSCFPPSKEFEPHLRS 1199
                    :|...:::::.:.|::      |...||           ||          |..|:.
plant  1150 ERVKKLADENKDLNDLVSSLEKKIDETEKKYEEASR-----------LC----------EERLKQ 1193

  Fly  1200 FMKQGTAQLQATPSLQRLE---------------RTLVNGP--RCQPPSLFELHAIRGRHPLRLD 1247
            .:...|..:....|:||||               :.|||..  |..|...|     .|..||.
plant  1194 ALDAETGLIDLKTSMQRLEEKVSDMETAEQIRRQQALVNSASRRMSPQVSF-----TGAPPLE-- 1251

  Fly  1248 IHLMDGQQ--------RRLQVDAASTAR------EAVNQLCQGMGLTDTFGFG---LVMSLNGKL 1295
                :|.|        ||...::...:|      |.|:.|.:.:.....|..|   ..:::...|
plant  1252 ----NGHQEPLAPIPSRRFGTESFRRSRIERQPHEFVDVLLKCVSKNIGFSHGKPVAALTIYKCL 1312

  Fly  1296 MP---LGAGQEHVLDAI-----SECEQRQLD---APW------KLYI----RKEMFATWYDPSMD 1339
            |.   ..|.:..:.|.|     |..|.::.|   |.|      .|::    .::..:|...|:..
plant  1313 MRWKIFEAEKTSIFDRIVPVFGSAIENQEDDNHLAYWLTNTSTLLFLLQRSLRQQSSTGSSPTKP 1377

  Fly  1340 PKATQLIYKQILNGLKCGEYRCRSEKDIAMVCALACFVEYGPGEILRLKPSEITAFVPSDLLAPG 1404
            |:.|. .:.::..|     :|..|..:::..........| |..:.:   .::||:|
plant  1378 PQPTS-FFGRMTQG-----FRSTSSPNLSTDVVQQVDARY-PALLFK---QQLTAYV-------- 1424

  Fly  1405 ERAIENWSRLIAATYEKSSYVKEEQNDLLLEAQKRAKEDICLFAHLSWPMRHSR---LFEVVRKE 1466
                |....:|...      ||.|.:.||....:..||..|..:.::.|.:.|.   ..:...:.
plant  1425 ----ETMYGIIREN------VKREVSSLLSSCIQSLKESSCDSSVVNSPSKSSEENLPAKSSEEN 1479

  Fly  1467 GPKLQSDELMLGINSAGLFLIDETEQVLASCCFSEVLKVHVESDDKLHVMTFQHVNFVLQ---CS 1528
            .||..|:|     ||......|::.|.|              |||.......|.|....:   .|
plant  1480 SPKKSSEE-----NSPKESSGDKSPQKL--------------SDDNSPSKEGQAVKSSEENSPAS 1525

  Fly  1529 SAQDANEVINYMLDNLRQRSSY-----------------GVALDPVVEGDLEDCLVLNPGDLIEF 1576
            |.|...|.:||:|  :..:.:|                 .|.|...:..:.|.|.| |.|  |:.
plant  1526 SWQSIIEFLNYIL--ITWKKNYVPLFLVQKMFSQTFQYINVQLFNSLLLEREYCTV-NMG--IKV 1585

  Fly  1577 EAGVTGAQLMAGNAQDCYRGCVNGQWGQFLAGNVRVLATLTKPSEKL 1623
            :||:...:.....|.:.:   |...|.:.......|:..:|:|...:
plant  1586 KAGLDELESWCSQATEEF---VGSSWDELKHTRQAVVLLVTEPKSTI 1629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo28B1	NP_723294.1	MYSc_Myo7	81..726	CDD:276832	278/658 (42%)
		IQ	765..785	CDD:197470	5/19 (26%)
		Atrophin-1	<820..>946	CDD:460830	29/147 (20%)
		MyTH4	1031..1239	CDD:470587	45/246 (18%)
		FERM1_F1_Myosin-VII	1243..1334	CDD:340612	24/128 (19%)
		B41	1248..1429	CDD:214604	37/218 (17%)
		PH-like	1454..1547	CDD:473070	22/98 (22%)
		MyTH4	1674..1819	CDD:214535
		FERM2_F1_Myosin-VII	1825..1919	CDD:340613
		B41	1827..2032	CDD:214604
		FERM_C2_MyoVII	2028..2121	CDD:270020
XIA	NP_171954.1	Myosin_N	8..51	CDD:460670	12/53 (23%)
		MYSc_Myo11	75..719	CDD:276835	278/658 (42%)
		PRK02224	<865..>1229	CDD:179385	85/451 (19%)
		MyosinXI_CBD	1278..1699	CDD:271259	78/407 (19%)