Protein Alignment Myo28B1 and ATM1

DIOPT Version :10

• Sequence 1: NP_723294.1
• Gene: Myo28B1 / 53515
• FlyBaseID: FBgn0040299
• Length: 2122
• Species: Drosophila melanogaster
• Sequence 2: NP_001154628.2
• Gene: ATM1 / 821534
• AraportID: AT3G19960
• Length: 1176
• Species: Arabidopsis thaliana
• Alignment Length: 1153
• Identity: 371/1153 - (32%)
• Similarity: 572/1153 - (49%)
• Gaps: 199/1153 - (17%)

  Fly     2 DAGYSPRKGEYVWVKPQNTTSEFAVPFGARIVRTEKTQTLVCDD-----RNK--QFWV------- 52
            |:..||..|..|:|:.|:.|.:  |..||..:...::......|     |.|  |.|:
plant    64 DSEDSPYSGHGVFVEEQSLTDD--VDSGAATMPLPQSDERRWSDTSAYARKKILQSWIQLPNGNW 126

  Fly    53 -----------------PAGDVLKAMHIT-------SQEDVEDMITLGDLQEYTILRNLQNRYAK 93
                             |.|.|:|.:..|       ..:.|:|::.|..|.|.::|.||..||.:
plant   127 ELGKILSTSGEESVISLPEGKVIKVISETLVPANPDILDGVDDLMQLSYLNEPSVLYNLNYRYNQ 191

  Fly    94 QLIYTYTGSMLVAINPYQILPIYTNREIQLYRNKSLAELPPHIFAISDNAFQRLQRLKENQCVVI 158
            .:|||..|.:|||:||::.:|:|.||.|:.||.||  ...||::||:|.|.:.:.|.:.||.::|
plant   192 DMIYTKAGPVLVAVNPFKEVPLYGNRYIEAYRKKS--NESPHVYAIADTAIREMIRDEVNQSIII 254

  Fly   159 ----------------SGESGAGKTESTKLILQYLAAISGKHSWIEQQIIEANPIMEAFGNAKTV 207
                            ||||||||||:.|:.:|||||:.| .|.||.:|::.|||:||||||||:
plant   255 RCICIHESMTYSISSSSGESGAGKTETAKIAMQYLAALGG-GSGIEYEILKTNPILEAFGNAKTL 318

  Fly   208 RNDNSSRFGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDERNYHIFYCMLAGLSTAERERL 272
            ||||||||||.|||.|:..|.|.||:||.:||||||:|..:..||:|||||.:.||.|.|.||:|
plant   319 RNDNSSRFGKLIEIHFSESGKISGAQIQTFLLEKSRVVQCAEGERSYHIFYQLCAGASPALREKL 383

  Fly   273 KLQEQSPSQYHYLAQGGCFTLPGRGDAKDFADIRAAMKVLSFKPEEVWSILSLLAAILHLGNLRF 337
            .|  .|..:|.||.|..|:::.|..||:.|..::.|:.::....|:..|:.::|||:|.|||:.|
plant   384 NL--TSAHEYKYLGQSNCYSINGVDDAERFHTVKEALDIVHVSKEDQESVFAMLAAVLWLGNVSF 446

  Fly   338 TATEVANLATAEIDDT-------------------PNLQRVAQLLGIPISALNAALTQRTIFVHG 383
            |..:..|......|::                   ..|..||:|:|..|:.|...|::|.:.|..
plant   447 TVIDNENHVEPVADESFLFHSLGSWCWKQECLLHNMCLSTVAKLIGCNINELTLTLSKRNMRVRN 511

  Fly   384 EHVTTSLSKEAAIEGRDAFVKSLYDGIFVRIVRRINETINKQVDQPMNSIGVLDIFGFENFDNNS 448
            :.:...|:...||:.|||..||:|..:|..:|.:||:::.....:...||.:|||:|||:||.||
plant   512 DTIVQKLTLPQAIDARDALAKSIYSCLFDWLVEQINKSLAVGKRRTGRSISILDIYGFESFDKNS 576

  Fly   449 FEQLCINYANENLQQFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMKPMNLMSLIDEE 513
            |||.|||||||.|||.|..|:||:||:||..:.|:|..::|:|||..|.|...||:.|:||:|||
plant   577 FEQFCINYANERLQQHFNRHLFKLEQEEYIQDGIDWTRVDFEDNQNCLSLFEKKPLGLLSLLDEE 641

  Fly   514 SKFPKGTDQTLLEKL--HVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPLGFLEKNRDSFSGD 576
            |.||.|||.||..||  |:|..:.....|||     ||.:.||||.|.|...||||||||....|
plant   642 STFPNGTDLTLANKLKQHLQSNSCFRGDKGK-----LFTVVHYAGEVTYETTGFLEKNRDLLHSD 701

  Fly   577 LRTLVQRSTNKYLVDIFPHEMPMDTAK--------------KQPTLCVKFRNSLDMLMRTLSQAH 627
            ...|:. |.:..|...|...|.:.:.|              ::.::..||::.|..||:.|....
plant   702 SIQLLS-SCSCLLPQAFASSMLIQSEKPVVGPLYKAGGADSQRLSVATKFKSQLFQLMQRLGNTT 765

  Fly   628 PYFIRCIKPNEYKEPKNFDKELCVRQLRYSGMMETARIRRAGY------PIRHAYRAFVERYRLL 686
            |:||||||||..:.|..:::.|.::|||..|::|.  :.:..|      .|.|.:....|.|
plant   766 PHFIRCIKPNNIQSPGVYEQGLVLQQLRCCGVLEV--LCKGPYKRFFIIAILHQFNILPEMY--- 825

  Fly   687 VPPVGPLEQCDCRKLARQICEVALPADSDRQYGKTKLFLRDEDDASLELQRSQLMLKSIVTIQRG 751
                                          |.|.||||.|......||..|:: .|..|:.:|..
plant   826 ------------------------------QVGYTKLFFRTGQIGVLEDTRNR-TLHGILRVQSS 859

  Fly   752 IRRVLFRRYMKRYREAIITVQRYWRGRLQRRKYQVMRQGFHRLGACIAAQQLTTKFTMVRCR--- 813
            .|....|..:|..:..|..:|.:.||...|:::..:|:. |:..|.|.: |:.:|...::.:
plant   860 FRGYQARCLLKELKRGISILQSFVRGEKIRKEFAELRRR-HKAAATIQS-QVKSKIARIQYKGIA 922

  Fly   814 --TIKLQALSRGYLVRK----------------DFQKKLLERRKQNQLKKEELLKLAKMKEAEE- 859
              ::.:|:..||:|||:                :..:.|::....::|::..|...|.::|.||
plant   923 DASVVIQSAIRGWLVRRCSGDIGWLKSGGAKTNELGEVLVKASVLSELQRRVLKAEAALREKEEE 987

  Fly   860 --LLRLQQLKEQKEREQREQQEKRLQEEQRLKAEAAARNALAMA----AVQQKRRTKPVKQEAPK 918
              :|: |:|::.:.|....:.:.:..||...|...:.:::|::|    ||:...|.......|..
plant   988 NDILQ-QRLQQYENRWSEYETKMKSMEEIWQKQMRSLQSSLSIAKKSLAVEDSARNSDASVNASD 1051

  Fly   919 APTLQARNSLPPPPTTLIVAAPLPTRPASA-VTRINTIPESPGTIDVESSKQMVDDVFRFL---- 978
            |....:.::.....|:..|.:.|  :|.|| ::.|..:.|     :.|...|:..|..:||
plant  1052 ATDWDSSSNQFRSQTSNGVGSRL--QPMSAGLSVIGRLAE-----EFEQRAQVFGDDAKFLVEVK 1109

  Fly   979 ------NDEPDAALRKLNNI------SSGDTIRLPKSVPNNIDTSDFS 1014
                  |.:||..||:|..:      ..|..:|..|.:.:.:.:.:.|
plant  1110 SGQVEANLDPDRELRRLKQMFETWKKDYGGRLRETKLILSKLGSEESS 1157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo28B1	NP_723294.1	MYSc_Myo7	81..726	CDD:276832	274/701 (39%)
		IQ	765..785	CDD:197470	5/19 (26%)
		Atrophin-1	<820..>946	CDD:460830	29/148 (20%)
		MyTH4	1031..1239	CDD:470587
		FERM1_F1_Myosin-VII	1243..1334	CDD:340612
		B41	1248..1429	CDD:214604
		PH-like	1454..1547	CDD:473070
		MyTH4	1674..1819	CDD:214535
		FERM2_F1_Myosin-VII	1825..1919	CDD:340613
		B41	1827..2032	CDD:214604
		FERM_C2_MyoVII	2028..2121	CDD:270020
ATM1	NP_001154628.2	MYSc_Myo8	179..835	CDD:276834	274/701 (39%)
		MAD	967..>1047	CDD:461677	18/80 (23%)