Protein Alignment Myo28B1 and XIG

DIOPT Version :10

• Sequence 1: NP_723294.1
• Gene: Myo28B1 / 53515
• FlyBaseID: FBgn0040299
• Length: 2122
• Species: Drosophila melanogaster
• Sequence 2: NP_179619.2
• Gene: XIG / 816548
• AraportID: AT2G20290
• Length: 1493
• Species: Arabidopsis thaliana
• Alignment Length: 1668
• Identity: 450/1668 - (26%)
• Similarity: 738/1668 - (44%)
• Gaps: 355/1668 - (21%)

  Fly    10 GEYVWVK-PQNT--TSEFAVPFGARI-VRTEKTQTLVCDDRN---KQFWVPAGDVLKAMHITSQE 67
            |..|||: |:..  ..|.....|..| |:....:|:|....|   |...||            ..
plant    20 GSIVWVQDPEEAWIDGEVVEVNGEDIKVQCTSGKTVVAKGSNTYPKDMEVP------------PS 72

  Fly    68 DVEDMITLGDLQEYTILRNLQNRYAKQLIYTYTGSMLVAINPYQILP-IYTNREIQLYRNKSLAE 131
            .|:||.||..|.|..:|:||::||....||||||::|:|:||::.|| :|.:..:..|:..:|.|
plant    73 GVDDMTTLAYLHEPGVLQNLKSRYYIDEIYTYTGNILIAVNPFKQLPNLYNDHMMAQYKGAALGE 137

  Fly   132 LPPHIFAISDNAFQRLQRLKENQCVVISGESGAGKTESTKLILQYLAAISGK----HSWIEQQII 192
            |.||.||::|.|::::.....:|.:::||||||||||:.|::::|||.:.|:    ...:|.|::
plant   138 LSPHPFAVADAAYRQMINEGISQSILVSGESGAGKTETAKMLMKYLAKMGGRAVSDRRTVEDQVL 202

  Fly   193 EANPIMEAFGNAKTVRNDNSSRFGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDERNYHIF 257
            |:||::|||||||||:|:|||||||::||:|..:|.|.||.|:.||||:||:...|..|||||.|
plant   203 ESNPVLEAFGNAKTVKNNNSSRFGKFVEIQFDQRGRISGAAIRTYLLERSRVCQVSDPERNYHCF 267

  Fly   258 YCMLAGLSTAERERLKLQEQSPSQYHYLAQGGCFTLPGRGDAKDFADIRAAMKVLSFKPEEVWSI 322
            | ||......::.:|||.:  |:::.||.|..|..|.|..|:|::...|.||.::....||..:|
plant   268 Y-MLCAAPPEDKRKLKLND--PTEFRYLNQSHCIKLDGVDDSKEYTKTREAMGIVGINLEEQEAI 329

  Fly   323 LSLLAAILHLGNLRFTATEVANLATAEIDDTPNLQRVAQLLGIPISALNAALTQRTIFVHGEHVT 387
            ..::||||||||:.|...|..:.:....:....|:..|:|......||..:|.:|.:....|.::
plant   330 FRVVAAILHLGNIEFAIGEEPDSSVPTDESKKYLKIAAELFMCDEQALEDSLCKRIMVTPEETIS 394

  Fly   388 TSLSKEAAIEGRDAFVKSLYDGIFVRIVRRINETINKQVDQPMNSIGVLDIFGFENFDNNSFEQL 452
            ..|...:|...|||..|.:|..:|..||.:||.:|.:..|. .:.||||||:|||:|..|||||.
plant   395 RCLDPNSAALSRDALAKFVYSRLFDWIVNKINNSIGQDPDS-KDMIGVLDIYGFESFKTNSFEQF 458

  Fly   453 CINYANENLQQFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMKPMNLMSLIDEESKFP 517
            |||..||.|||.|..|:.||||:||..|.|.|..|.|.||:.:|:||..|...:::|:||...||
plant   459 CINLTNEKLQQHFTQHVLKMEQEEYTKEEIEWSQITFPDNRYVLELIEKKRGGIIALLDEACMFP 523

  Fly   518 KGTDQTLLEKLHVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPLGFLEKNRDSFSGDLRTLVQ 582
            :.|.:|..:||:....:...:.|.|.::|. |.|.||||.|.|....|||||:|....:.:.|:.
plant   524 RSTHKTFSQKLYETLKDNKYFSKPKLSRTD-FTICHYAGDVTYQTEQFLEKNKDYVVAEHQALLG 587

  Fly   583 RSTNKYLVDIFPHEMPM-DTAKKQ---PTLCVKFRNSLDMLMRTLSQAHPYFIRCIKPNEYKEPK 643
            .|...::..:||   |: :.|.||   .::..:|:..|..|:..|:...|::|||:|||...:|.
plant   588 ASRCTFIAGLFP---PLVEDANKQSKFSSIASQFKQQLASLIEGLNTTEPHYIRCVKPNNLLKPS 649

  Fly   644 NFDKELCVRQLRYSGMMETARIRRAGYPIRHAYRAFVERYRLLVPPV---GPLEQCDCRKLARQI 705
            .|:.:..::|||..|:|||.|:.|||||.|..:..|::|:.:|....   ...|:..|:||...:
plant   650 IFENQNSLQQLRCGGVMETIRVCRAGYPTRKHFDEFLDRFGILDSATLDKSSDEKAACKKLLETV 714

  Fly   706 CEVALPADSDRQYGKTKLFLRDEDDASLELQRSQLMLKSIVTIQRGIRRVLFRRYMKRYREAIIT 770
                  ..:..|.||||:||:....|.|:.:|::::.::...||...|..|.|:.....|.|.|.
plant   715 ------GLNGFQIGKTKVFLKAGQMAELDDRRTEVLGRAACIIQWKFRSYLTRQSFIMLRNAAIN 773

  Fly   771 VQRYWRGRLQRRKYQVMRQ------------------------------GFHRLGACIAAQQLTT 805
            :|..:||::.|.:::.:|:                              |...:.|.:..::.|.
plant   774 IQAVYRGQVARYRFENLRREAAALKIQRALRIHLDRKRSYIEAVVTVQSGLRGMAARVVLRRKTK 838

  Fly   806 KFTMVR--CRTIKLQ----ALSRGYLVRKDFQKKLLERRKQNQLKKEE----LLKLAKMKEAEEL 860
            ..|:::  ||.::.:    .|.:..:..:...:..|.|::..:||.:.    :|:.||...||::
plant   839 ATTVIQSHCRRLRAELHYKKLKKAAITTQSAWRARLARKELRKLKTDARDTVVLQAAKSMLAEKV 903

  Fly   861 LRLQQLKEQKEREQREQQEKRLQEEQRL-KAEAAARNALAMAAVQ---QKRRTKPVKQ-EAPKAP 920
                     :|...|...|||::.:..: ||:..|:..||:..:|   ::.:...:|: ||.|.
plant   904 ---------EELTWRLDLEKRMRVDMEVSKAQENAKLQLALEEIQLQFEETKVSLLKEVEAAKK- 958

  Fly   921 TLQARNSLPPPPTTLIVAAPLPTRPASAVTRINTIPESPGTIDVESSKQMVDDVFRFLNDEPDAA 985
                            .||.:|.  ...|..::|:.....|.:.|..|.:|..: ....||.:..
plant   959 ----------------TAAIVPV--VKEVPVVDTVLMEKLTSENEKLKSLVTSL-ELKIDETEKK 1004

  Fly   986 LRKLNNISSGDTIRLPKSV--PNNIDTSDFSYLKYAATYFGGGATAQHE-RKPLKKSLLKHEHPI 1047
            ..:...||..   ||.|::  .|.||.     ||          ||.|. .:.||:..|::....
plant  1005 FEETKKISEE---RLKKALDAENKIDN-----LK----------TAMHNLEEKLKEVKLENNFLK 1051

  Fly  1048 DEMASKAIWLTILRFMGDLPDVVSSPTLHVFDNENLMSDLASLLNTSDSYKPRL----------- 1101
            :.:.:..:.....||:       |:| |....|....|:.:.|.....:..||:
plant  1052 ESVLTTPVKTASGRFL-------STP-LKNLQNGLFTSEESQLSGAEFTTPPRIQESGSDTKSRG 1108

  Fly  1102 ------------FVRQSQRRI----PKPLASGEKEAQEFYQ---HWLNVP---TSHLEKIHFIIG 1144
                        .:....:.:    .||:|     |...|:   ||.:..   |:..:::..:||
plant  1109 SHIDPQHEDVDALINSVTKNVGFSQGKPVA-----AFTIYKCLLHWKSFEAERTNVFDRLVQMIG 1168

  Fly  1145 HGIIKNSLRDEILAQICKQLYLNPSRSSYSRGWLLLSLCLSCFPPSKEFEPHLRSFMKQ------ 1203
                 ::::||.          |.:..:|   ||..:..|              .||.|
plant  1169 -----SAIKDED----------NDANLAY---WLSNTSTL--------------LFMLQQSLKSG 1201

  Fly  1204 --GTAQLQATPSLQRLERTLVNGPRCQPPSLFELHAIRGRHPLRLDIHLMDGQQRRLQV------ 1260
              |...|:.:||   |.|.:..|.|  .|:...:..:..:.|.   :|..  ||....|
plant  1202 GTGATPLRQSPS---LVRWMTKGFR--SPAAEAIRPVDAKDPA---LHFK--QQLEAYVEKILGI 1256

  Fly  1261 --DAASTAREAVNQLCQGMGLTDTFGFGLVMSLNGKLMPLGAGQEHV--LDAISECEQRQLDAPW 1321
              |........|..||  :....||....::|:.    .....|:.:  |||:
plant  1257 IWDNLKKELNTVLALC--IQAPKTFKGNALISIT----TANYWQDIIEGLDAL------------ 1303

  Fly  1322 KLYIRKEMFATWYDPSMDPKATQLIYKQ---ILNGLKCGEYRCRSEKDIAMVCALACFVEYGPGE 1383
             |...||.|       :.|...|.|:.|   ::|...|.....|.:.         |
plant  1304 -LSTLKESF-------VPPVLIQKIFSQAFSLINVQVCNSLVTRPDN---------C-------- 1343

  Fly  1384 ILRLKPSEITAFVPSDLLAPGERAIENWSRLIAATYEKSSYVKEEQNDLLLEAQKRAKEDI-CLF 1447
                      :|:..:.|..|...:|.|.......|..||:          :..|..::.: .|.
plant  1344 ----------SFINGEYLKSGLEKLEKWCCETKEEYAGSSW----------DELKHTRQAVGFLL 1388

  Fly  1448 AHLSWPMRHSRLFEVVRKEGPKLQ-----------SDELMLGINSAGLFLIDETEQVLASCCFSE 1501
            .|..:.:.:.   |:.....|.||           .||:   .|:..:     ::.|:||
plant  1389 IHKKYNISYD---EIANDLCPNLQIQQHFKLCTLYKDEI---YNTKSV-----SQDVIAS----- 1437

  Fly  1502 VLKVHVESDDKLHVMTFQHVNFVLQCSSAQDANEVINYMLDNL 1544
            :..|..:|.|           |:|:    :|::.:|:..:|:|
plant  1438 MTGVMTDSSD-----------FLLK----EDSSNIISLSIDDL 1465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo28B1	NP_723294.1	MYSc_Myo7	81..726	CDD:276832	256/656 (39%)
		IQ	765..785	CDD:197470	7/19 (37%)
		Atrophin-1	<820..>946	CDD:460830	28/134 (21%)
		MyTH4	1031..1239	CDD:470587	43/249 (17%)
		FERM1_F1_Myosin-VII	1243..1334	CDD:340612	20/100 (20%)
		B41	1248..1429	CDD:214604	35/193 (18%)
		PH-like	1454..1547	CDD:473070	19/102 (19%)
		MyTH4	1674..1819	CDD:214535
		FERM2_F1_Myosin-VII	1825..1919	CDD:340613
		B41	1827..2032	CDD:214604
		FERM_C2_MyoVII	2028..2121	CDD:270020
XIG	NP_179619.2	COG5022	12..1421	CDD:227355	435/1594 (27%)
		MYSc_Myo11	86..729	CDD:276835	256/656 (39%)