Protein Alignment Myo28B1 and myo3b

DIOPT Version :10

• Sequence 1: NP_723294.1
• Gene: Myo28B1 / 53515
• FlyBaseID: FBgn0040299
• Length: 2122
• Species: Drosophila melanogaster
• Sequence 2: XP_073768512.1
• Gene: myo3b / 564573
• ZFINID: ZDB-GENE-070706-2
• Length: 1333
• Species: Danio rerio
• Alignment Length: 1002
• Identity: 331/1002 - (33%)
• Similarity: 505/1002 - (50%)
• Gaps: 173/1002 - (17%)

  Fly    59 KAMHITSQEDVEDMITLGDLQEYTILRNLQNRYAKQLIYTYTGSMLVAINPYQILPIYTNREIQL 123
            |.:.|.|..| :|::.|..|.|.||:.:||.||....||||.|.:|:|:||:|.|.||:.:..:|
Zfish   374 KTLIIESCPD-DDLVNLELLDEETIIAHLQKRYQDLQIYTYVGDILIALNPFQNLSIYSPQFSKL 437

  Fly   124 YRNKSLAELPPHIFAISDNAFQRLQRLKENQCVVISGESGAGKTESTKLILQYLAAISGK--HSW 186
            |.....:..||||||.:|.|:|.:..|.::||::||||||||||||..||:|:|..: ||  :..
Zfish   438 YHGMKRSTNPPHIFATADAAYQSMVTLCKDQCIIISGESGAGKTESAHLIVQHLTFL-GKANNRT 501

  Fly   187 IEQQIIEANPIMEAFGNAKTVRNDNSSRFGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDE 251
            :.::|::.||::||||||.|..||||||||||:|::|||.||:.||:|.:|||||||::.|:..|
Zfish   502 LREKILQVNPLVEAFGNACTAINDNSSRFGKYLEMKFTPTGAVMGAKISEYLLEKSRVIKQATGE 566

  Fly   252 RNYHIFYCMLAGLSTAER-ERLKLQEQSPSQYHYLAQGGCF--TLPGRGDAKDFADIRAAMKVLS 313
            :|:||||.:.|||...:. .:.||..::..:|.....|...  .:..:...:.|..|:...:::.
Zfish   567 KNFHIFYYIYAGLYHQDNLRKYKLPNKTAPRYIDCVNGKVMQDIISSKLYKEQFDAIQDCFRIIG 631

  Fly   314 FKPEEVWSILSLLAAILHLGNLRF-TATEVANLATAEIDDTPNLQRVAQLLGIPISALNAALTQR 377
            |..|||.|:..:|||||:.||:.| :|:.......:|:.::..|...|.||.|....|..|||..
Zfish   632 FTEEEVNSVYRILAAILNTGNIEFASASSQHQSDKSEVPNSEALDNAAALLSIGSEELQEALTSH 696

  Fly   378 TIFVHGEHVTTSLSKEAAIEGRDAFVKSLYDGIFVRIVRRINETINKQ-----VDQPMNSIGVLD 437
            .:...||.:..:.:.:.|...|||..|:||..:|..||.|||..:...     .:..|| :|:||
Zfish   697 CVVTRGETIIRTNTVDKATVVRDAMSKALYGRLFSWIVNRINALLQPDTNICAAESGMN-VGILD 760

  Fly   438 IFGFENFDNNSFEQLCINYANENLQQFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMK 502
            |||||||..|||||||||.|||.:|.:|..|||.:||.|||:|.::...:|::||:.|||:...|
Zfish   761 IFGFENFKKNSFEQLCINIANEQIQFYFNQHIFALEQIEYQSEGVDVSLVEYEDNRPILDMFLQK 825

  Fly   503 PMNLMSLIDEESKFPKGTDQTLLEKLHVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPLGFLE 567
            ||.|:||:||||:||:.|||||::|......|:..::..:.  ...|||:||||.|:||..||||
Zfish   826 PMGLLSLLDEESRFPQATDQTLVDKFQDNLRNKYFWIPKRV--ELCFGIQHYAGQVLYNVSGFLE 888

  Fly   568 KNRDSFSGDLRTLVQRSTN-------------------------------------------KYL 589
            ||||:...|:..:::.|.|                                           |||
Zfish   889 KNRDTLPADIVVVLRTSENRLLQQLFSSPLTKTGNLATSRARVTAASRSLPPQLNSGRNKSPKYL 953

  Fly   590 VDIFPHEM---PMDTAK-KQPTLCVKFRNSLDMLMRTLSQAHPYFIRCIKPNEYKEPKNFDKELC 650
            :.:...||   |.:|.. ::.|:...||.||..|:..:....|:|:||||||:.::...|:||..
Zfish   954 LKVDTMEMMRHPEETTNMRRQTVASYFRYSLMDLLSKMVVGTPHFVRCIKPNDDRQALRFNKERV 1018

  Fly   651 VRQLRYSGMMETARIRRAGYPIRHAYRAFVERYRLLV-----PPVGPLEQCDCRKLARQICEVAL 710
            :.||||:|::||..|||.||..|...:.||.||..|.     .|.|..|..           :.:
Zfish  1019 MVQLRYTGILETVNIRRQGYSHRILIQEFVNRYYYLAFRAHQMPEGSKENA-----------III 1072

  Fly   711 PADSDRQY---GKTKLFLRDEDDASLELQRSQLMLKS----IVTIQR------GIRRVLFRRYMK 762
            ...:...|   |.||:||:     ...:::..|||:.    :|.:|.      |.||  :||..:
Zfish  1073 LQKAKLDYWVVGNTKVFLK-----YYHVEQLNLMLREVIARVVLMQAYTKGWLGARR--YRRERE 1130

  Fly   763 RYREAIITVQRYWRGRLQRRKYQVMRQGFHRLGACIAAQQLTTKFTMVRCRTIKLQALSRGYLVR 827
            :.|...:.:|..|||.:.|:..:::::...:                   ..:::|::.|||.||
Zfish  1131 KRRNGAVVIQSAWRGHVARQNLKLIKREREQ-------------------AAVQIQSVYRGYRVR 1176

  Fly   828 KDFQKK-------LLERRKQNQLKKEELL----------------KLAKMKEAEELLRLQ----- 864
            ||:::.       ..:|...|....|:::                |..|..::.|...|.
Zfish  1177 KDYKQSRQWTGQPSSKRSSTNHSPDEKVVSVSADSGIGSSDASVPKTDKQSDSRERAPLSKQGPT 1241

  Fly   865 -QLKEQKEREQREQQEKRLQEEQRLKAEAAARNALAMAAVQQKRRTKPVK--------------- 913
             :|.:.:...:|.||.|.|...:    ::...|.|..:...|..:.||.|
Zfish  1242 LKLHQHRSPRRRGQQPKLLNSPE----DSLYYNHLNRSLDYQGSKRKPRKLGQIKLLDGEDEYYQ 1302

  Fly   914 -----QEAPKAPTLQARNSLP--PPPT 933
                 :..|:...|...:..|  .|||
Zfish  1303 LLSTIEAVPEEDVLTGTSPNPTSTPPT 1329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo28B1	NP_723294.1	MYSc_Myo7	81..726	CDD:276832	273/710 (38%)
		IQ	765..785	CDD:197470	6/19 (32%)
		Atrophin-1	<820..>946	CDD:460830	32/165 (19%)
		MyTH4	1031..1239	CDD:470587
		FERM1_F1_Myosin-VII	1243..1334	CDD:340612
		B41	1248..1429	CDD:214604
		PH-like	1454..1547	CDD:473070
		MyTH4	1674..1819	CDD:214535
		FERM2_F1_Myosin-VII	1825..1919	CDD:340613
		B41	1827..2032	CDD:214604
		FERM_C2_MyoVII	2028..2121	CDD:270020
myo3b	XP_073768512.1	None