Protein Alignment Myo28B1 and myo1ea

DIOPT Version :10

• Sequence 1: NP_723294.1
• Gene: Myo28B1 / 53515
• FlyBaseID: FBgn0040299
• Length: 2122
• Species: Drosophila melanogaster
• Sequence 2: XP_005168983.2
• Gene: myo1ea / 555285
• ZFINID: ZDB-GENE-030131-5127
• Length: 1117
• Species: Danio rerio
• Alignment Length: 1036
• Identity: 323/1036 - (31%)
• Similarity: 485/1036 - (46%)
• Gaps: 204/1036 - (19%)

  Fly    62 HITSQEDVEDMITLGDLQEYTILRNLQNRYAKQLIYTYTGSMLVAINPYQILPIYTNREIQLYRN 126
            |...|..|:||:.|..:.|..|:.||:.||....|:||.|.:|:::||::.:|.:..:||::|:.
Zfish    14 HNVKQSGVDDMVLLSKINEDAIVENLKKRYMDDYIFTYIGPVLISVNPFKQMPYFGEKEIEMYQG 78

  Fly   127 KSLAELPPHIFAISDNAFQRLQRLKENQCVVISGESGAGKTESTKLILQYLAAISG-----KHSW 186
            .:..|.||||:|::||.::.:...:|||||:||||||||||.:.|.|:.|::.:||     :|
Zfish    79 AAQYENPPHIYALADNMYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISKVSGGGPRVQH-- 141

  Fly   187 IEQQIIEANPIMEAFGNAKTVRNDNSSRFGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDE 251
            ::..|:::||::|||||||||||:||||||||.||:|:..|...|.:|..:||||||:|.::..|
Zfish   142 VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGE 206

  Fly   252 RNYHIFYCMLAGLSTAERERLKLQEQSPSQYHYLAQGGCFTLPGRGDAKDFADIRAAMKVLSFKP 316
            |::||||.::.|.|..::..|.:  .|...|.||.|.|.:.:....|..||.:...||.|:....
Zfish   207 RSFHIFYQLIEGASGDQKSSLGI--TSLDYYTYLNQSGSYKVDDINDKHDFQETLHAMDVIGISG 269

  Fly   317 EEVWSILSLLAAILHLGNLRFTATEVANLATAEIDDTPNLQRVAQLLGIPISALNAALTQRTIFV 381
            .:...:|.::|.||||||:.|  .|..|.|..|.|:.  |...|.||||....|...||.|.  :
Zfish   270 IDRTMVLQIVAGILHLGNINF--REAGNYAAVENDEF--LAFPAFLLGIDQERLKEKLTSRK--M 328

  Fly   382 HG------EHVTTSLSKEAAIEGRDAFVKSLYDGIFVRIVRRINETINKQVDQPMNSIGVLDIFG 440
            .|      |.:..:|:.|.|...|||..|:|:..:|..:|..||:.:.|: .|.:| ||||||:|
Zfish   329 DGKWGGKSESIDVTLNVEQACFTRDALSKALHSRVFDYLVESINKAMVKE-HQELN-IGVLDIYG 391

  Fly   441 FENFDNNSFEQLCINYANENLQQFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMK--P 503
            ||.|..|.|||.|||:.||.|||.|:....|.|||||..|.|.|..||:.:|:.:.|||..|  |
Zfish   392 FEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQDEYVQEGIRWTQIEYFNNKIVCDLIESKINP 456

  Fly   504 MNLMSLIDE-----ESKFPKGTDQTLLEKLHVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPL 563
            ..:||::|:     .:| .:|.|||:|:||.:|..|...:    .:....|.|.||||.|.|:..
Zfish   457 PGIMSILDDVCATMHAK-GEGADQTMLQKLRMQINNHEHF----NSWNQGFIIHHYAGKVSYDAE 516

  Fly   564 GFLEKNRDSFSGDLRTLVQRSTNKYLVDIFPHEMPMDTAKKQPTLCVKFRNSLDMLMRTLSQAHP 628
            ||.|:|||....||..|:|.|...::..:||..:..:...:..|...|.:...:.|:.||.:..|
Zfish   517 GFCERNRDVLFTDLIELMQSSEIAFIRALFPENLNAEKKGRPTTAGSKIKKQANDLVSTLMKCTP 581

  Fly   629 YFIRCIKPNEYKEPKNFDKELCVRQLRYSGMMETARIRRAGYPIRHAYRAFVERYRLLVPPVGPL 693
            ::||||||||.|:||::::.....|:.|.|:.|..|:|||||..|..:|.|:.||.:|.....|.
Zfish   582 HYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFRKFLNRYAILTKESWPT 646

  Fly   694 EQCDCRK----LARQICEVALPADSDR-QYGKTKLFLRDEDDASLELQRSQLMLKSIVTIQRGIR 753
            .:.|.::    |.|.:     ..|.|: |.|.||:|::..:        |..:|:.       .|
Zfish   647 WRGDEKQGVLHLLRSV-----NMDQDQYQLGHTKIFIKAPE--------SLFLLEE-------TR 691

  Fly   754 RVLFRRYMKRYREAIITVQRYWRGRLQRRKYQVMRQGFHRLGACIAAQQLTTKFTMVRCRTIKLQ 818
            ...|..|.:       |:|..||....|:||..||:
Zfish   692 ERKFDGYAR-------TIQTAWRKYCARKKYVQMRE----------------------------- 720

  Fly   819 ALSRGYLVRKDFQKKLLERRKQNQLKKEELLKLAKMKEAEELLRLQQLKEQKEREQREQQEKR-- 881
                                                 ||.:||       ..::|:|.....|
Zfish   721 -------------------------------------EASDLL-------LNKKERRRHSLNRNF 741

  Fly   882 ------LQEEQRLKAEAAARNALAMAAVQQK--RRTKPVKQE---APKAPTLQARNSLPPPPTTL 935
                  :.:...|:.....|..:..|....|  ||.|.:|::   .||:..|..|..:...|...
Zfish   742 VGDYLGMDDRPELRQFVGKREKIDFADKVNKFDRRFKSIKRDLILTPKSVYLIGREKVKQGPEKG 806

  Fly   936 IVAAPLPTRPASAVTRINTIPESPGTIDVE-----SSKQMVDDVFRFLNDEPDAALRKLNNISSG 995
            :|...|..:                 ||||     |...:.||......||.|:.|..:
Zfish   807 LVKEVLKRK-----------------IDVEKILAVSLSTLQDDFMILHEDEYDSLLECV------ 848

  Fly   996 DTIRLPKSVPNNIDTSDFSYLKYAATYFGGGATAQHERKPLKKSLLKHEHPIDEMASKAIW 1056
                        ..|...|.|           ..::|.:..:|..||:.:.::....|..|
Zfish   849 ------------FKTEFISLL-----------ARRYEERTQRKLPLKYSNTMEMKLKKEKW 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo28B1	NP_723294.1	MYSc_Myo7	81..726	CDD:276832	260/667 (39%)
		IQ	765..785	CDD:197470	6/19 (32%)
		Atrophin-1	<820..>946	CDD:460830	22/138 (16%)
		MyTH4	1031..1239	CDD:470587	6/26 (23%)
		FERM1_F1_Myosin-VII	1243..1334	CDD:340612
		B41	1248..1429	CDD:214604
		PH-like	1454..1547	CDD:473070
		MyTH4	1674..1819	CDD:214535
		FERM2_F1_Myosin-VII	1825..1919	CDD:340613
		B41	1827..2032	CDD:214604
		FERM_C2_MyoVII	2028..2121	CDD:270020
myo1ea	XP_005168983.2	None