DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myo28B1 and Myo3a

DIOPT Version :9

Sequence 1:	NP_723294.1	Gene:	Myo28B1 / 53515	FlyBaseID:	FBgn0040299	Length:	2122	Species:	Drosophila melanogaster
Sequence 2:	XP_574090.6	Gene:	Myo3a / 498806	RGDID:	1560083	Length:	268	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	56/265 - (21%)
Similarity:	97/265 - (36%)	Gaps:	69/265 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   995 GDTIRLPKSVPNNIDTSDFSYLKYAATYFGGGATAQHERKPLKKS---LLKHEHPIDEMASKAIW 1056
            |.|| :..:.|:..||.:.:......||  |.......:|..:|:   :|...|.|||.....
  Rat     6 GKTI-IFDNFPDPSDTWEITETIGKGTY--GKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAE-- 65

  Fly  1057 LTILRFMGDLPDVVSSPTLHVFDNENLMSDLASLL-------NTSDSYKPRLFVRQSQRRIPKPL 1114
            ..|||.:.|.|:||....:: |..:.:..|...|:       :.:|..|.  |:::.:|.....:
  Rat    66 YNILRTLSDHPNVVRFYGIY-FKKDKINGDKLWLVLELCNGGSVTDLVKG--FLKRGERMSEPII 127

  Fly  1115 ASGEKEAQEFYQHWLNVPTSHLEKIHFIIGHGIIKNS---------------------------- 1151
            |....||....||..:..|.|.:    :.|:.|:..:
  Rat   128 AYILHEALMGLQHLHSNKTIHRD----VKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGT 188

  Fly  1152 ---LRDEILAQICKQLYLNPSRSSYSRGWLLLSLCLSCF------PPSKEFEPHLRSFMK---QG 1204
               :..|::|  |:| .|:.:..:....|   ||.::..      ||..|..| :|:..|   .|
  Rat   189 PFWMAPEVIA--CEQ-QLDTTYDARCDTW---SLGITAIELGDGDPPLAELHP-MRALFKIPRSG 246

  Fly  1205 TAQLQ 1209
            ..|:|
  Rat   247 DQQVQ 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myo28B1	NP_723294.1	MYSc	62..737	CDD:214580
		MYSc_Myo7	81..726	CDD:276832
		IQ	765..785	CDD:197470
		DUF4355	827..>887	CDD:290964
		MyTH4	1031..1239	CDD:295320	47/229 (21%)
		B41	1248..1429	CDD:214604
		FERM_N	1248..>1288	CDD:286467
		FERM_B-lobe	1342..1429	CDD:271216
		PH-like	1454..1547	CDD:302622
		MyTH4	1674..1819	CDD:214535
		B41	1827..2032	CDD:214604
		FERM_N	1829..>1877	CDD:286467
		FERM_M	1936..2032	CDD:278785
		FERM_C2_MyoVII	2028..2121	CDD:270020
Myo3a	XP_574090.6	PKc_like	2..258	CDD:419665	56/265 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910