Protein Alignment Myo28B1 and Myo1d

DIOPT Version :10

• Sequence 1: NP_723294.1
• Gene: Myo28B1 / 53515
• FlyBaseID: FBgn0040299
• Length: 2122
• Species: Drosophila melanogaster
• Sequence 2: XP_036012676.1
• Gene: Myo1d / 338367
• MGIID: 107728
• Length: 1010
• Species: Mus musculus
• Alignment Length: 745
• Identity: 282/745 - (37%)
• Similarity: 435/745 - (58%)
• Gaps: 70/745 - (9%)

  Fly    90 RYAKQLIYTYTGSMLVAINPYQILPIYTNREIQLYRNKSLAELPPHIFAISDNAFQRLQRLKENQ 154
            |:.|..|||:.|.::|::|||::|.||....::.|:.:.|.|.|||:|||:|.|::.::|..::.
Mouse    36 RFEKGRIYTFIGEVVVSVNPYKVLNIYGRDTVEQYKGRELYERPPHLFAIADAAYKAMKRRSKDT 100

  Fly   155 CVVISGESGAGKTESTKLILQYLAAIS--GKHSWIEQ---QIIEANPIMEAFGNAKTVRNDNSSR 214
            |::|||||||||||::|.|:||:|||:  .:.:.||:   .::::|.::||||||||.|||||||
Mouse   101 CIMISGESGAGKTEASKYIMQYIAAITNPSQRAEIERVKNMLLKSNCVLEAFGNAKTNRNDNSSR 165

  Fly   215 FGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDERNYHIFYCMLAGLSTAERERLKLQEQSP 279
            ||||::|.|..:|...|..|..|||||||::.|...||::|.||.:|.|.|......|.|| :|.
Mouse   166 FGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHSLHLQ-KSL 229

  Fly   280 SQYHYLAQGGCFTLPGRGDAKDFADIRAAMKVLSFKPEEVWSILSLLAAILHLGNLRFTATEVAN 344
            |.|:|:..|.... ....||.:|..:..||||:.|||||:.::..:||.|||||||:|.
Mouse   230 SSYNYIRVGAQLK-SSINDAAEFKVVADAMKVIGFKPEEIQTVYKILAVILHLGNLKFI------ 287

  Fly   345 LATAEID-DTPNLQR------VAQLLGIPISALNAALTQRTIFVHGEHVTTSLSKEAAIEGRDAF 402
                 :| |||.::.      :|:||......:..||..||:....:.:....:::.|..|||||
Mouse   288 -----VDGDTPLIENGKVVSVIAELLSTKADMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAF 347

  Fly   403 VKSLYDGIFVRIVRRINETIN-KQVDQPMNS----IGVLDIFGFENFDNNSFEQLCINYANENLQ 462
            .|::|:.:|..||.|||:.|. |..|..::.    ||||||:|||.||||||||.||||.||.||
Mouse   348 AKAIYERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQ 412

  Fly   463 QFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMKPMNLMSLIDEE-SKFPKGTDQTLLE 526
            |.|:..:.|.||:|||.|.|.|:||::.:||.|:||:..:...:::::|:. ....|.||...||
Mouse   413 QLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDGMFLE 477

  Fly   527 KLHVQHGNRSIYVKGKTTQTSL-------FGIRHYAGVVMYNPLGFLEKNRDSFSGDLRTLVQRS 584
            .|:.:.|....:...||..:..       |.||||||.|:|:.:||::||:|:...|.:.|:..|
Mouse   478 ALNSKLGKHGHFSSRKTCASDKILEFDRDFRIRHYAGDVVYSAIGFIDKNKDTLFQDFKRLMYNS 542

  Fly   585 TNKYLVDIFPH-EMPMDTAKKQP-TLCVKFRNSLDMLMRTLSQAHPYFIRCIKPNEYKEPKNFDK 647
            :|..|.:::|. ::.:....|:| |....|:||:..|:..|:...||::||||||:.|.|:.||.
Mouse   543 SNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDD 607

  Fly   648 ELCVRQLRYSGMMETARIRRAGYPIRHAYRAFVERYRLLVPPVGPLEQCDCRKLARQICEVALPA 712
            |.|..|:.|.|::|..|:||||:..|..|..|:.||:::.....|...              ||:
Mouse   608 ERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHD--------------LPS 658

  Fly   713 D--------------SDRQYGKTKLFLRDEDDA-SLELQRSQLMLKSIVTIQRGIRRVLFRRYMK 762
            |              .|..|||:|:|:|..... :||..|:|::::.::.:|:..|..|.|...|
Mouse   659 DKEAVKKLIERCGFQDDVAYGKSKIFIRTPRTLFTLEELRAQMLVRVVLFLQKVWRGTLARMRYK 723

  Fly   763 RYREAIITVQRYWRGRLQRRKYQVMRQGFH 792
            |.:.|:..::.|.|.:::...::|.|: ||
Mouse   724 RTKAALTIIRYYRRYKVKSYIHEVARR-FH 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo28B1	NP_723294.1	MYSc_Myo7	81..726	CDD:276832	264/676 (39%)
		IQ	765..785	CDD:197470	3/19 (16%)
		Atrophin-1	<820..>946	CDD:460830
		MyTH4	1031..1239	CDD:470587
		FERM1_F1_Myosin-VII	1243..1334	CDD:340612
		B41	1248..1429	CDD:214604
		PH-like	1454..1547	CDD:473070
		MyTH4	1674..1819	CDD:214535
		FERM2_F1_Myosin-VII	1825..1919	CDD:340613
		B41	1827..2032	CDD:214604
		FERM_C2_MyoVII	2028..2121	CDD:270020
Myo1d	XP_036012676.1	MYSc_Myo1	36..686	CDD:276829	264/676 (39%)
		Myosin_TH1	807..1000	CDD:461801