Protein Alignment Myo28B1 and Myo3b

DIOPT Version :10

• Sequence 1: NP_723294.1
• Gene: Myo28B1 / 53515
• FlyBaseID: FBgn0040299
• Length: 2122
• Species: Drosophila melanogaster
• Sequence 2: NP_796350.2
• Gene: Myo3b / 329421
• MGIID: 2448580
• Length: 1333
• Species: Mus musculus
• Alignment Length: 1119
• Identity: 355/1119 - (31%)
• Similarity: 539/1119 - (48%)
• Gaps: 257/1119 - (22%)

  Fly    30 ARIVRTEKTQTLVCDDRNKQFWVPAGDVLKAMHITSQEDVE---------DMITLGDLQEYTILR 85
            |::::.:|.:..|...|:::           ||......||         |::.|..|.|.||:.
Mouse   324 AKVLQDQKHRNPVAKTRHER-----------MHTGRPHRVEDAGKCCLEDDLVNLEVLDEDTIIY 377

  Fly    86 NLQNRYAKQLIYTYTGSMLVAINPYQILPIYTNREIQLYRNKSLAELPPHIFAISDNAFQRLQRL 150
            .||.|||..|||||.|.:|:|:||:|.|.||:.:..:||.....:..||||||.:|||:|.|...
Mouse   378 WLQKRYADALIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRSSNPPHIFASADNAYQCLVTF 442

  Fly   151 KENQCVVISGESGAGKTESTKLILQYLAAISGK--HSWIEQQIIEANPIMEAFGNAKTVRNDNSS 213
            .::||:|||||||:|||||..||:|:|..: ||  :..:.|:|::.|.::||||||:|..|||||
Mouse   443 SKDQCIVISGESGSGKTESAHLIVQHLTFL-GKADNQTLRQKILQVNSLVEAFGNARTAINDNSS 506

  Fly   214 RFGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDERNYHIFYCMLAGLSTAER-ERLKLQEQ 277
            |||||:|:.|||.||:.||||.:|||||||::.|:..|:|:||||.:.|||...:: ...:|.|:
Mouse   507 RFGKYLEMMFTPTGAVMGARISEYLLEKSRVIQQAAGEKNFHIFYYIYAGLYHQKKLAEFRLPEE 571

  Fly   278 SPSQYHYLAQGGCFTLPGRGD-------AKD-----FADIRAAMKVLSFKPEEVWSILSLLAAIL 330
            .|.:|          :.|..:       :|:     |..|:...|::.|..:||.|:..:||.||
Mouse   572 KPPRY----------IAGETERVMQDITSKESYRTQFEAIQHCFKIIGFADKEVHSVYRILAGIL 626

  Fly   331 HLGNLRFTATEVANLATAEIDDTPN---LQRVAQLLGIPISALNAALTQRTIFVHGEHVTTSLSK 392
            ::|::.|.|  :::....:..:.||   |:..|.:|.|....|..|||...:...||.:..:.:.
Mouse   627 NIGSIEFAA--ISSQHQTDKSEVPNPEALENAACVLCISSEELQEALTSHCVVTRGETIVRANTV 689

  Fly   393 EAAIEGRDAFVKSLYDGIFVRIVRRINETI--NKQV---DQPMNSIGVLDIFGFENFDNNSFEQL 452
            :.|.:.|||..|:||..:|..||.|||..:  :|.:   :..|| :|:|||||||:|..||||||
Mouse   690 DRAEDVRDAMSKALYGRLFSWIVNRINTLLQPDKNICSAEDRMN-VGILDIFGFEDFQRNSFEQL 753

  Fly   453 CINYANENLQQFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMKPMNLMSLIDEESKFP 517
            |||.|||.:|.:|..|:|.:||.||:||.::...::::||:.:||:...||:.|::|:||||:||
Mouse   754 CINIANEQIQYYFNQHVFALEQMEYKNEGVDAVLVQYEDNRPLLDMFLQKPLGLLALLDEESRFP 818

  Fly   518 KGTDQTLLEKLHVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPLGFLEKNRDSFSGDLRTLVQ 582
            :||||||::|.. .:.....:.:.|..:. .|||:||||.|:|:..|.||||||:...|:..:::
Mouse   819 QGTDQTLVDKFE-DNLRCKFFWRPKGVEL-CFGIQHYAGPVLYDASGVLEKNRDTLPADVVVVLR 881

  Fly   583 RSTNKYLVDIF-------------------------PH--------------EMPMDTAK-KQPT 607
            .|.||.|..:|                         ||              ..|.:|.. |:.|
Mouse   882 TSENKLLQQLFSIPLTKTGNLAQTRAKITASSRSLPPHFSAGRAKVDTLEVIRHPEETTNMKRQT 946

  Fly   608 LCVKFRNSLDMLMRTLSQAHPYFIRCIKPNEYKEPKNFDKELCVRQLRYSGMMETARIRRAGYPI 672
            :...||.||..|:..:....|:||||||||:.::...|.::..:.|||.:|::||..|||.||..
Mouse   947 MASYFRYSLMDLLSKMVVGQPHFIRCIKPNDDRKALQFSQDRVLAQLRSTGILETVSIRRQGYSH 1011

  Fly   673 RHAYRAFVERYRLL------VPPVGPLEQCDCRKLARQICEVALPADSDRQY---GKTKLFLRDE 728
            |..:..||:||..|      .||... |.|           ||:...|...:   ||||:||:
Mouse  1012 RIFFEEFVKRYYYLAFRAHQTPPANK-ESC-----------VAILEKSRLDHWVLGKTKVFLK-- 1062

  Fly   729 DDASLELQRSQLMLKSIVTIQRGIRRVLFRRYMKRYREAIITVQRYWRGRLQRRKYQVMRQGFHR 793
               ...:::..|:|:.::.     |.|:.:.|.|.:    :..:||.|.:.:|.|
Mouse  1063 ---YYHVEQLNLLLREVMG-----RVVMLQAYTKGW----LGARRYKRAKEKREK---------- 1105

  Fly   794 LGACIAAQQLTTKFTMVRCRTIKLQALSRGYLVRKDFQKKLLERRKQNQLKKEELLKLAKMKEAE 858
             ||                  |.:|:..|||    |.::||    ||...::.|       .||.
Mouse  1106 -GA------------------ITIQSAWRGY----DARRKL----KQRSRRRSE-------SEAH 1136

  Fly   859 ELLRLQQLKEQKEREQREQQEKRLQEEQRLKAEAAARNALAMAAVQQKRRTKPVKQEAPKAPTLQ 923
            ....||...:||.......:..|..||       .:||.             |.:.:....|..|
Mouse  1137 IHTVLQTTPDQKYCPDSGGESNRGHEE-------TSRNC-------------PAEADTDGHPQAQ 1181

  Fly   924 ARNSLPPPPT---------------TLI--------VAAPLPTRPASAVTRINTIPES--PGTID 963
            :      |||               |:.        |:..|....|||..|::...:|  ||:.:
Mouse  1182 S------PPTGCDVTSGHADTAAGYTVAELSVAGTDVSPSLVYHTASAHQRLSPCEDSLKPGSEE 1240

  Fly   964 VESSKQMVDDVFRFLNDEPDAALRKLNNISSGDTIRLPKSVPNNIDTSDFSYLKYAATYFGGGAT 1028
            ..|.||.             |..|:...         ||.:.:..||..::.|.....|.|.
Mouse  1241 GLSQKQR-------------APRRRCQQ---------PKMLSSPEDTMYYNQLNGTLEYQGS--- 1280

  Fly  1029 AQHERKPLKKSLLK 1042
               :|||.|...:|
Mouse  1281 ---QRKPRKLGQIK 1291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo28B1	NP_723294.1	MYSc_Myo7	81..726	CDD:276832	274/716 (38%)
		IQ	765..785	CDD:197470	5/19 (26%)
		Atrophin-1	<820..>946	CDD:460830	29/148 (20%)
		MyTH4	1031..1239	CDD:470587	5/12 (42%)
		FERM1_F1_Myosin-VII	1243..1334	CDD:340612
		B41	1248..1429	CDD:214604
		PH-like	1454..1547	CDD:473070
		MyTH4	1674..1819	CDD:214535
		FERM2_F1_Myosin-VII	1825..1919	CDD:340613
		B41	1827..2032	CDD:214604
		FERM_C2_MyoVII	2028..2121	CDD:270020
Myo3b	NP_796350.2	STKc_myosinIIIB_N	20..310	CDD:270808
		MYSc_Myo3	373..1062	CDD:276830	274/716 (38%)