Protein Alignment Myo28B1 and Myo95E

DIOPT Version :10

• Sequence 1: NP_723294.1
• Gene: Myo28B1 / 53515
• FlyBaseID: FBgn0040299
• Length: 2122
• Species: Drosophila melanogaster
• Sequence 2: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Alignment Length: 1010
• Identity: 236/1010 - (23%)
• Similarity: 367/1010 - (36%)
• Gaps: 298/1010 - (29%)

  Fly    71 DMITLGDLQEYTILRNLQNRYAKQLIYTYTGSMLVAINPYQILPIYTNREIQLYRNKSLAELPPH 135
            |.:.|.:|.|.:.:.|:..||.:..||||.|:.:||:|||..:..::...::.|.:|.:.:||||
  Fly     9 DSVLLENLSEDSFINNIHQRYKRDHIYTYIGTSVVALNPYHHISEHSLDNVRNYGDKGIFQLPPH 73

  Fly   136 IFAISDNAFQRLQRLKENQCVVISGESGAGKTESTKLILQYLA---------------------- 178
            |:.:::.|:|.|:...|:|||:::|||||||||:.|:|:.:|.
  Fly    74 IYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNVLRKQSSTS 138

  Fly   179 ----------------------------------------------------------------- 178
                                                                             
  Fly   139 SASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAESIERQSRRH 203

  Fly   179 -----------------AISG----------------KH-------------------------- 184
                             .|||                ||
  Fly   204 MREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGSPKYAVPTV 268

  Fly   185 ----------------------------------------------------SWIEQQIIEANP- 196
                                                                :.:.|...|:.|
  Fly   269 YGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQHSTESQPE 333

  Fly   197 ----------------------------------------------------------------- 196
                                                                             
  Fly   334 RERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQRMRECVTC 398

  Fly   197 ---IMEAFGNAKTVRNDNSSRFGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDERNYHIFY 258
               .:||.|||.|::|:||||:||..:|....:|...|..|..|:|||:||......|||:||||
  Fly   399 ADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFKGDPMGVHITHYMLEKTRITDPIIGERNFHIFY 463

  Fly   259 CMLAGLSTAERERLKLQEQSPSQYHYLAQGGCFTLPGRGDAKDFADIRAAMKVLSFKPEEVWSIL 323
            .:|.|......:.|||. ::..:|..|..    |.....|..:|...:.::.||....||..||.
  Fly   464 QLLLGADLQLLKSLKLY-RNVEKYELLRN----TTAMEEDRMNFHYTKRSLDVLGLSCEESNSIF 523

  Fly   324 SLLAAILHLGNLRFT-ATEVANLATAEIDDTPNLQRVAQLLGIPISALNAALTQ-RTIFVHGEHV 386
            .::|.:|.|||..|. .|.:......::.:...:|..||||.:....|...||: .:.....|.|
  Fly   524 RVIAVVLKLGNFIFVPITNIDGTEGCQVSNVYEVQETAQLLNMEAQILINCLTRANSTNSAQEDV 588

  Fly   387 TTSLSKEAAIEGRDAFVKSLYDGIFVRIVRRINETINKQVDQPMNSIGVLDIFGFENFDNNSFEQ 451
            ...:....|...|:...::||..:|..:|.:|||::..  .|...::.:||.:|||..|:|||||
  Fly   589 GCEMDARQAATNRNTLCRTLYSRLFTWLVNKINESLKS--TQREKNLALLDFYGFEALDHNSFEQ 651

  Fly   452 LCINYANENLQQFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMKPMNLMSLIDEESKF 516
            ..|||:.|.:.|.||.|:.:.||:.|..|.:.|..|::.||:.|.:||......::|||:|...
  Fly   652 FAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELIDKPSYGILSLINEPHL- 715

  Fly   517 PKGTDQTLLEKLHVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPLGFLEKNRDSFSGDLRTLV 581
             ...|..||.......|:.:....|  :.:..|.|||||.||.|:...|||||.|.....:....
  Fly   716 -NSNDALLLRVQQCCAGHPNFMTTG--SNSMCFQIRHYASVVNYSIHRFLEKNSDMLPKYISAAF 777

  Fly   582 QRSTNKYLVDIFPHEMPMDTAKKQP-TLCVKFRNSLDMLMRTLSQAHPYFIRCIKPNEYKEPKNF 645
            .:|....:..:||...|.....|:| ||....|..|..|:..:.....:::.||||||.|:|..|
  Fly   778 YQSKLSLVQSLFPEGNPRRQVTKKPSTLSSNIRTQLQTLLAIVKHRRSHYVFCIKPNEGKQPHQF 842

  Fly   646 DKELCVRQLRYSGMMETARIRRAGYPIRHAYRAFVERYRLLVPPVGPLEQ--CDCRKLARQICEV 708
            |..|...|:||..:|....:.|.|:.....:..|..||:||.....|...  .....:|..|..:
  Fly   843 DMALVQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRYKLLNSLTWPHFHGGSQVEGIALIIRNL 907

  Fly   709 ALPADSDRQYGKTKLFLRDEDDA-SLELQRSQLMLKSIVTIQRGIRRVLFRRYMKRYREAIITVQ 772
            .||: ::...|...:|:|..... .||..|...:.:..|.||...|....|:..:|.|.:.:.:.
  Fly   908 PLPS-AEFTIGTKNVFVRSPRTVYELEQFRRLRISELAVLIQTMFRMYHARKRFQRMRHSQMIIS 971

  Fly   773 RYWRGRLQRR-------------KYQVMRQGFHRL 794
            ..||...:.|             .|:|.|:.:..|
  Fly   972 SAWRTWRECRFGIPFTGRRHLWSLYRVAREEYRSL 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo28B1	NP_723294.1	MYSc_Myo7	81..726	CDD:276832	214/916 (23%)
		IQ	765..785	CDD:197470	4/32 (13%)
		Atrophin-1	<820..>946	CDD:460830
		MyTH4	1031..1239	CDD:470587
		FERM1_F1_Myosin-VII	1243..1334	CDD:340612
		B41	1248..1429	CDD:214604
		PH-like	1454..1547	CDD:473070
		MyTH4	1674..1819	CDD:214535
		FERM2_F1_Myosin-VII	1825..1919	CDD:340613
		B41	1827..2032	CDD:214604
		FERM_C2_MyoVII	2028..2121	CDD:270020
Myo95E	NP_001027208.1	Motor_domain	3..>123	CDD:473979	43/113 (38%)
		Motor_domain	<403..937	CDD:473979	170/545 (31%)
		Myosin_TH1	1092..1288	CDD:461801