Protein Alignment Myo28B1 and Myo1g

DIOPT Version :10

• Sequence 1: NP_723294.1
• Gene: Myo28B1 / 53515
• FlyBaseID: FBgn0040299
• Length: 2122
• Species: Drosophila melanogaster
• Sequence 2: XP_006514763.1
• Gene: Myo1g / 246177
• MGIID: 1927091
• Length: 1039
• Species: Mus musculus
• Alignment Length: 755
• Identity: 274/755 - (36%)
• Similarity: 406/755 - (53%)
• Gaps: 77/755 - (10%)

  Fly    90 RYAKQLIYTYTGSMLVAINPYQILPIYTNREIQLYRNKSLAELPPHIFAISDNAFQRLQRLKENQ 154
            ::.|..||||.|.:||::||||.||:|....|..|:.:.|.|.|||::|:::.|::.::|...:.
Mouse    53 KFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAKYQGRELYERPPHLYAVANAAYKAMKRRSRDT 117

  Fly   155 CVVISGESGAGKTESTKLILQYLAAISGKHSWIEQQ-----IIEANPIMEAFGNAKTVRNDNSSR 214
            |:||||||||||||::|.|:||:||::......|.:     ::::..::||||||:|.||.||||
Mouse   118 CIVISGESGAGKTEASKHIMQYIAAVTNPSQRAEVERVKNVLLKSTCVLEAFGNARTNRNHNSSR 182

  Fly   215 FGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDERNYHIFYCMLAGLSTAERERLKLQEQSP 279
            ||||::|.|..:|...|..|..|||||||::.|...|||:|.||.:|.|....|.:.|.| |::|
Mouse   183 FGKYMDINFDFKGDPVGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDQELQGLHL-ERNP 246

  Fly   280 SQYHYLAQGGCFTLPGR----GDAKDFADIRAAMKVLSFKPEEVWSILSLLAAILHLGNLRFTAT 340
            :.|::..||....:...    .|.|....:..||:::.|.|:||.||..:|||||||||:.|..|
Mouse   247 AVYNFTRQGAGLNMGVHNALDSDEKSHQGVMEAMRIIGFSPDEVESIHRILAAILHLGNIEFVET 311

  Fly   341 EV--ANLATAEIDDTPNLQRVAQLLGIPISALNAALTQRTIFVHG-EHVTTSLSKEAAIEGRDAF 402
            |.  ......|:.|...:..||:|...|...:...|..||:...| |.:..|.:...|...|||.
Mouse   312 EENGPQKGGLEVADEALVGYVAKLTATPRDLVLRTLLARTVASGGREVIEKSHTVAEASYARDAC 376

  Fly   403 VKSLYDGIFVRIVRRINETINKQVDQPM-----NSIGVLDIFGFENFDNNSFEQLCINYANENLQ 462
            .|::|..:|..:|.:||..:..:...|.     ..||||||:|||.|..|||||.||||.||.||
Mouse   377 AKAMYQRLFEWVVNKINSIMEPRNRDPRCDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQ 441

  Fly   463 QFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMKPMNLMSLIDEE-SKFPKGTDQTLLE 526
            |.|:..|.|.||:||:.|.|.||.||:.:|..|::|:......:::::||. |.....||:..|:
Mouse   442 QLFIQLILKQEQEEYEREGIAWQTIEYFNNATIVELVEQPHRGILAVLDEACSTAGPITDRIFLQ 506

  Fly   527 KLHVQHGNRSIYVKGK---TTQTSLFG----IRHYAGVVMYNPLGFLEKNRDSFSGDLRTLVQRS 584
            .|...|.:...|...:   |.:|..||    |:||||.|.|:..||::|||||...|.:.|:..|
Mouse   507 TLDTHHRHHPHYSSRQLCPTDKTMEFGRDFQIKHYAGDVTYSVEGFIDKNRDSLFQDFKRLLYNS 571

  Fly   585 TNKYLVDIFPH-EMPMDTAKKQP-TLCVKFRNSLDMLMRTLSQAHPYFIRCIKPNEYKEPKNFDK 647
            .:..|..::|. :..:....|:| |....|:||:..|:..|:...|:::|||||||.|.....|:
Mouse   572 VDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRCIKPNEDKVAGRLDE 636

  Fly   648 ELCVRQLRYSGMMETARIRRAGYPIRHAYRAFVERYRLLVPPVGPLEQCDCRKLARQICEVALP- 711
            ..|..|:.|.|::|..|:||||:..|..|..|:.||::                   .||...|
Mouse   637 AHCRHQVEYLGLLENVRVRRAGFASRQPYPRFLLRYKM-------------------TCEYTWPN 682

  Fly   712 --ADSDRQ----------------YGKTKLFLRDEDD-ASLELQRSQLMLKSIVTIQRGIRRVLF 757
              ..|||.                :|.:|||:|.... .:||..|::|:...::.:|:..|..|.
Mouse   683 HLLGSDRDAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKAWRGTLA 747

  Fly   758 RRYMKRYREAIITVQRYWRG--------RLQRRKYQVMRQ 789
            |.:.:|.| ||.|:.|::|.        .|||| :|..||
Mouse   748 RWHCRRLR-AIYTIMRWFRRHKVRAHLIELQRR-FQAARQ 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo28B1	NP_723294.1	MYSc_Myo7	81..726	CDD:276832	251/681 (37%)
		IQ	765..785	CDD:197470	10/27 (37%)
		Atrophin-1	<820..>946	CDD:460830
		MyTH4	1031..1239	CDD:470587
		FERM1_F1_Myosin-VII	1243..1334	CDD:340612
		B41	1248..1429	CDD:214604
		PH-like	1454..1547	CDD:473070
		MyTH4	1674..1819	CDD:214535
		FERM2_F1_Myosin-VII	1825..1919	CDD:340613
		B41	1827..2032	CDD:214604
		FERM_C2_MyoVII	2028..2121	CDD:270020
Myo1g	XP_006514763.1	MYSc_Myo1	52..715	CDD:276829	251/681 (37%)
		Myosin_TH1	836..1007	CDD:461801