DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37C2 and UGT76D1

DIOPT Version :9

Sequence 1:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_180216.1	Gene:	UGT76D1 / 817189	AraportID:	AT2G26480	Length:	452	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	102/532 - (19%)
Similarity:	187/532 - (35%)	Gaps:	165/532 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 FSSHSPSHLIIHMSVAKALVKAGHNVTVVSMLKPKVTHKDIH-----LIVVPMKE--EQERIMED 84
            |..|.||    .|::|..|...|.::|:|   :.:...|||.     :....:|:  .:..:...
plant    16 FQGHLPS----MMNLASYLSSQGFSITIV---RNEFNFKDISHNFPGIKFFTIKDGLSESDVKSL 73

  Fly    85 QMTEMAGQKNSLVSTMYR-LLTSMDVMINAQAELLSDPRFQRIYETKFDLMILGYFINDFQLGVA 148
            .:.|...:.||:...:.: .||:.|.::                    |.:|...|:. |...||
plant    74 GLLEFVLELNSVCEPLLKEFLTNHDDVV--------------------DFIIYDEFVY-FPRRVA 117

  Fly   149 HKLKVPVIINWMSAPVPAIDKYTGNPSELSYVPLMGTVATQPMGFLKRTENALKSLLFEFI--FV 211
            ..:.:|.::...|:...:|.:..             .:..|..|.|...:  .:|.|.|.:  |.
plant   118 EDMNLPKMVFSPSSAATSISRCV-------------LMENQSNGLLPPQD--ARSQLEETVPEFH 167

  Fly   212 VFDYKLTRIYNDVFPEQDMP--------TLKELRKNISMAFVGSHLISEG--------------- 253
            .|.:|            |:|        .|..|.:|:|.....|.:|...
plant   168 PFRFK------------DLPFTAYGSMERLMILYENVSNRASSSGIIHNSSDCLENSFITTAQEK 220

  Fly   254 ------PIRPL--------VPALIEIGGIQVKDKPDPLPKDIDQFISNAKQGAVFLSLGSNVKSS 304
                  |:.||        .|:|.|    :.::..:.|.|       ......:::|:||...:.
plant   221 WGVPVYPVGPLHMTNSAMSCPSLFE----EERNCLEWLEK-------QETSSVIYISMGSLAMTQ 274

  Fly   305 TVRPEIVQIIFKVLSELKENVIWKW-----------------EDLENTPGNSSNILYKNWLPQDD 352
            .:  |.|::   .:..::.|..:.|                 |....|..:....:.| |.||.:
plant   275 DI--EAVEM---AMGFVQSNQPFLWVIRPGSINGQESLDFLPEQFNQTVTDGRGFVVK-WAPQKE 333

  Fly   353 ILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALME---KSGYGLALDLLSITED 414
            :|.|.....|..|.|.....|:...||||:..|..|||..|..||.   ::.|.:..:|   ...
plant   334 VLRHRAVGGFWNHGGWNSCLESISSGVPMICRPYSGDQRVNTRLMSHVWQTAYEIEGEL---ERG 395

  Fly   415 SLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQL 479
            ::..|::.::.:|:.::        .|.|....|:.|    |..:..:|       |.|.:   |
plant   396 AVEMAVRRLIVDQEGQE--------MRMRATILKEEV----EASVTTEG-------SSHNS---L 438

  Fly   480 NNLDIYALIVTI 491
            ||| ::|:::.|
plant   439 NNL-VHAIMMQI 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	94/506 (19%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	99/526 (19%)
UGT76D1	NP_180216.1	Glycosyltransferase_GTB-type	6..445	CDD:415824	100/526 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000