Protein Alignment Ugt37C2 and UGT2A3

DIOPT Version :9

• Sequence 1: NP_001260516.1
• Gene: Ugt37C2 / 53513
• FlyBaseID: FBgn0040262
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_011530549.1
• Gene: UGT2A3 / 79799
• HGNCID: 28528
• Length: 533
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 143/511 - (27%)
• Similarity: 251/511 - (49%)
• Gaps: 38/511 - (7%)

  Fly    33 SHLIIHMSVAKALVKAGHNVTVVSMLKP------KVTHKDIHLIVVPM--KEEQERIMEDQMTEM 89
            ||.:....:.:.|:..||.|||::..||      |.:.....::.:|.  .||.|..::..:..:
Human    34 SHWLNVKVILEELIVRGHEVTVLTHSKPSLIDYRKPSALKFEVVHMPQDRTEENEIFVDLALNVL 98

  Fly    90 AGQKNSLVSTMYRLLTSMDVMINAQAEL--------LSDPRFQRIYETKFDLMILGYFINDFQLG 146
            .|     :||...::...|..:..:..|        .:....:::.||.:|:|::...|....|
Human    99 PG-----LSTWQSVIKLNDFFVEIRGTLKMMCESFIYNQTLMKKLQETNYDVMLIDPVIPCGDL- 157

  Fly   147 VAHKLKVPVIINWMSAPVPAIDKYTGN-PSELSYVPLMGTVATQPMGFLKRTENALKSLLFEFIF 210
            :|..|.||.::....:....:::..|. |:.|||||:..|..|..|.||:|.:|::.|:||.|..
Human   158 MAELLAVPFVLTLRISVGGNMERSCGKLPAPLSYVPVPMTGLTDRMTFLERVKNSMLSVLFHFWI 222

  Fly   211 VVFDYKL-TRIYNDVFPEQDMPTLKELRKNISMAFVGSHLISEGPIRPLVPALIEIGGIQVKDKP 274
            ..:||.. ...|:......  .||.|......:..:.::...|.| :|..|....:||:..| ..
Human   223 QDYDYHFWEEFYSKALGRP--TTLCETVGKAEIWLIRTYWDFEFP-QPYQPNFEFVGGLHCK-PA 283

  Fly   275 DPLPK------DIDQFI-SNAKQGAVFLSLGSNVKSSTVRPEIVQIIFKVLSELKENVIWKWEDL 332
            ..|||      :::.|: |:.:.|.|..||||..::  |..|...||...|:::.:.|:|:::..
Human   284 KALPKINFYLQEMENFVQSSGEDGIVVFSLGSLFQN--VTEEKANIIASALAQIPQKVLWRYKGK 346

  Fly   333 ENTPGNSSNILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALM 397
            :.:...::..|| :|:||:|:|.||.||.||||.|..||.||.|||||||.:||||||..|.|.|
Human   347 KPSTLGANTRLY-DWIPQNDLLGHPKTKAFITHGGMNGIYEAIYHGVPMVGVPIFGDQLDNIAHM 410

  Fly   398 EKSGYGLALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQ 462
            :..|..:.::..::|.:.|..||:.|:.:..||:...:.|.::.|:|:......|||.|:::||:
Human   411 KAKGAAVEINFKTMTSEDLLRALRTVITDSSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHK 475

  Fly   463 GAPNLQSPSVHMNFIQLNNLDIYALIVTILVLFVLLTRLVAKIVWNKFGGKAKISQ 518
            ||.:|:|.:..:.:.|..::|:...::..:...:.|..........||....||.:
Human   476 GAKHLRSAAHDLTWFQHYSIDVIGFLLACVATAIFLFTKCFLFSCQKFNKTRKIEK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	134/458 (29%)
		UDPGT	33..515	CDD:278624	141/506 (28%)
UGT2A3	XP_011530549.1	UDPGT	24..528	CDD:278624	141/506 (28%)
		egt	<267..498	CDD:223071	82/234 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150240
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740