Protein Alignment Ugt37C2 and UGT1A10

DIOPT Version :9

• Sequence 1: NP_001260516.1
• Gene: Ugt37C2 / 53513
• FlyBaseID: FBgn0040262
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_061948.1
• Gene: UGT1A10 / 54575
• HGNCID: 12531
• Length: 530
• Species: Homo sapiens
• Alignment Length: 515
• Identity: 153/515 - (29%)
• Similarity: 265/515 - (51%)
• Gaps: 46/515 - (8%)

  Fly    33 SHLIIHMSVAKALVKAGHNVTVVSMLKPKVT---HKDIHLIVVPMKEEQERIMEDQMTEMA---- 90
            ||.....||.:.|:..||.|.||   .|:|:   .:.::..|.......  .:|||..|..
Human    36 SHWFTMQSVVEKLILRGHEVVVV---MPEVSWQLERSLNCTVKTYSTSY--TLEDQNREFMVFAH 95

  Fly    91 GQKNSLVSTMYRLLTS-----MDVMINAQAELLSDPRF-QRIYETKFDLMILGYFINDFQLGVAH 149
            .|..:...:::.||.|     :|:..:....|.:|.:. :.:.|:.||.:.|..| :...|.||.
Human    96 AQWKAQAQSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPF-DTCGLIVAK 159

  Fly   150 KLKVPVIINWMSAPVPAIDKYTGNPSELSYVP--LMGTVATQPMGFLKRTENALKSL---LF-EF 208
            ...:|.::.........:::....|:.|||||  |:|  .:..|.|.:|..|.:..|   || ::
Human   160 YFSLPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLG--FSDAMTFKERVWNHIVHLEDHLFCQY 222

  Fly   209 IFVVFDYKLTRIYNDVFPEQDMPTLKELRKNISMAFVGSHLISEGPIRPLVPALIEIGGIQVKDK 273
            :|    .....|.:::.  |...|..:|..:.|:..:.:..:.:.| :|::|.:|.||||.. .:
Human   223 LF----RNALEIASEIL--QTPVTAYDLYSHTSIWLLRTDFVLDYP-KPVMPNMIFIGGINC-HQ 279

  Fly   274 PDPLPKDIDQFI-SNAKQGAVFLSLGSNVKSSTVRPEIVQIIFKVLSELKENVIWKWEDLENTPG 337
            ..|||.:.:.:| ::.:.|.|..||||.|  |.:..:....|...|.::.:.|:|::..  ..|.
Human   280 GKPLPMEFEAYINASGEHGIVVFSLGSMV--SEIPEKKAMAIADALGKIPQTVLWRYTG--TRPS 340

  Fly   338 NSSN--ILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKS 400
            |.:|  ||.| ||||:|:|.||.|:.||||||..|:.|:..:|||||.:|:||||..||..||..
Human   341 NLANNTILVK-WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETK 404

  Fly   401 GYGLALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQGAP 465
            |.|:.|::|.:|.:.|.:|||.|:.::.||:.|.:.|:|::|||:......|||.|:::||:|||
Human   405 GAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAP 469

  Fly   466 NLQSPSVH-MNFIQLNNLDIYALIVTILVLFVLLTRLVAKIVWNK-FGGKAKISQTKKKQ 523
            :|: |:.| :.:.|.::||:...::.:::....:|.......:.| .|.|.::.:..|.:
Human   470 HLR-PAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	142/455 (31%)
		UDPGT	33..515	CDD:278624	152/505 (30%)
UGT1A10	NP_061948.1	UDPGT	26..521	CDD:278624	152/506 (30%)
		egt	<258..504	CDD:223071	94/253 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150388
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740