Protein Alignment Ugt37C2 and UGT2B28

DIOPT Version :9

• Sequence 1: NP_001260516.1
• Gene: Ugt37C2 / 53513
• FlyBaseID: FBgn0040262
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_444267.1
• Gene: UGT2B28 / 54490
• HGNCID: 13479
• Length: 529
• Species: Homo sapiens
• Alignment Length: 517
• Identity: 155/517 - (29%)
• Similarity: 266/517 - (51%)
• Gaps: 60/517 - (11%)

  Fly    33 SHLIIHMSVAKALVKAGHNVTVV----SMLKPKVTHKDIHLIVVP---MKEEQERIMEDQMTEMA 90
            ||.:...::.|.||:.||.|||:    |:|........:.|.|.|   .|.|.|.|:..|:...:
Human    34 SHWMNMKTILKELVQRGHEVTVLASSASILFDPNDAFTLKLEVYPTSLTKTEFENIIMQQVKRWS 98

  Fly    91 G-QKNSL---VSTMYRLLTSM-DVMINAQAELLSDPR-FQRIYETKFDLMILGYFINDFQLG--V 147
            . ||:|.   .|....:|... |:..|...:::|:.: .:::.|::||::....|   |..|  :
Human    99 DIQKDSFWLYFSQEQEILWEFHDIFRNFCKDVVSNKKVMKKLQESRFDIIFADAF---FPCGELL 160

  Fly   148 AHKLKVPVIINWMSAPVPAIDKYTGN---PSELSYVPLMGTVATQPMGFLKRTENALKSLLFEFI 209
            |..|.:|.:.:....|...|::::|.   |.  ||:|::.:..:..|.|::|.:|.:..|.|:|.
Human   161 AALLNIPFVYSLCFTPGYTIERHSGGLIFPP--SYIPVVMSKLSDQMTFMERVKNMIYVLYFDFW 223

  Fly   210 FVVFDY-KLTRIYNDVF--PEQDMPTLKE----LRKNISMAFVGSHLISEGPIRPLVPALIEIGG 267
            |.:.|. |..:.|::|.  |.....|:.:    |.:| |.:|...|        |.:|.:..:||
Human   224 FQMCDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRN-SWSFQFPH--------PFLPNIDFVGG 279

  Fly   268 IQVKDKPDPLPKDIDQFI-SNAKQGAVFLSLGSNVKSSTVRPEIVQIIFKVLSELKENVIWKWED 331
            :..| ...||||::::|: |:.:.|.|..||||.:.:.|.  |...:|...|:::.:.|:|:::
Human   280 LHCK-PAKPLPKEMEEFVQSSGENGVVVFSLGSVISNMTA--ERANVIATALAKIPQKVLWRFD- 340

  Fly   332 LENTPGNSSNI------LYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQ 390
                 ||..:.      ||| |:||:|:|..|.|:.||||.|..||.||.|||:|||.:|:|.||
Human   341 -----GNKPDALGLNTRLYK-WIPQNDLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQ 399

  Fly   391 PGNAALMEKSGYGLALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWT 455
            |.|.|.|:..|..:.||..:::...|.:|||.|:.:..||:.:.:.|.:..|:|:......|||.
Human   400 PDNIAHMKAKGAAVRLDFHTMSSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWI 464

  Fly   456 EYILRHQGAPNLQSPSVHMNFIQLNNLDI--YALIVTILVLFVLLTRLVAKIVWNKFGGKAK 515
            |:::.|:||.:|:..:..:.:.|.::||:  :.|.....|:|| :|:......| ||..|.|
Human   465 EFVMCHKGAKHLRVAARDLTWFQYHSLDVIGFLLACVATVIFV-VTKFCLFCFW-KFARKGK 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	141/465 (30%)
		UDPGT	33..515	CDD:278624	154/515 (30%)
UGT2B28	NP_444267.1	UDPGT	24..525	CDD:278624	155/517 (30%)
		egt	<269..506	CDD:223071	84/246 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150519
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740